C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caspase recruitment domain family, member 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198286 CARD11 9606 - 7:2906141-3043945 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355508 CARD11-013 2919480-2930060 protein_coding
  ENST00000356408 CARD11-012 2947576-3043845 protein_coding
  ENST00000396946 CARD11-011 2906141-3043945 protein_coding
  ENST00000480332 CARD11-014 2917290-2923040 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355508ENST00000356408ENST00000396946
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355508 N/A N/A 0.245±0.00 N/A N/A N/A N/A N/A N/A N/A 0.067±0.00 N/A N/A N/A
ENST00000356408 N/A N/A N/A N/A N/A N/A N/A N/A 1.529±0.00 1.151±0.00 N/A N/A N/A N/A
ENST00000396946 0.139±0.00 11.159±0.00 0.146±0.00 0.197±0.00 0.510±0.00 0.114±0.00 0.044±0.00 0.394±0.00 0.188±0.02 2.470±2.19 0.154±0.00 4.573±5.44 0.416±0.18 0.211±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RS CIL_0007RS_0001 VISTA 7:2311652-2915186
CIL_0002MC CIL_0002MC_0001 CGP 7:2728112-3043945
CIL_0002M9 CIL_0002M9_0001 CGP 7:2906141-4269000

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001772 IEA immunological synapse
GO:0001819 IMP positive regulation of cytokine production
GO:0004385 NAS guanylate kinase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0007165 IEA signal transduction
GO:0030890 IEA positive regulation of B cell proliferation
GO:0031295 IDA T cell costimulation
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042101 IDA T cell receptor complex
GO:0042102 IEA positive regulation of T cell proliferation
GO:0042981 IEA regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045061 IEA thymic T cell selection
GO:0045086 IEA positive regulation of interleukin-2 biosynthetic process
GO:0045087 TAS innate immune response
GO:0045121 IDA membrane raft
GO:0045577 IEA regulation of B cell differentiation
GO:0045580 IEA regulation of T cell differentiation
GO:0046939 NAS nucleotide phosphorylation
GO:0050700 IPI CARD domain binding
GO:0050776 IEA regulation of immune response
GO:0050852 TAS T cell receptor signaling pathway
GO:0050870 IEA positive regulation of T cell activation
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052741 card11 caspase recruitment domain family, member 11 protein_coding Danio_rerio
ENSMUSG00000036526 Card11 caspase recruitment domain family, member 11 protein_coding Mus_musculus

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