C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: negative elongation factor complex member E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204356 NELFE 9606 - 6:31952087-31959110 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375425 NELFE-013 31952229-31958852 protein_coding
  ENST00000375429 NELFE-001 31952087-31959110 protein_coding
  ENST00000426722 NELFE-009 31954820-31958859 protein_coding
  ENST00000436289 NELFE-010 31954389-31958571 protein_coding
  ENST00000441998 NELFE-007 31953758-31958957 protein_coding
  ENST00000444811 NELFE-012 31952229-31958960 protein_coding
  ENST00000454913 NELFE-011 31954304-31958479 protein_coding
  ENST00000481121 NELFE-002 31952228-31958962 retained_intron
  ENST00000488426 NELFE-003 31952228-31958919 retained_intron
  ENST00000491139 NELFE-006 31955065-31958965 retained_intron
  ENST00000492185 NELFE-004 31952227-31959038 retained_intron
  ENST00000492539 NELFE-005 31954773-31958968 nonsense_mediated_decay
  ENST00000494956 NELFE-008 31955084-31958954 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375425ENST00000375429ENST00000441998ENST00000444811ENST00000454913ENST00000481121
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375425 N/A N/A N/A N/A N/A N/A N/A N/A 4.293±0.00 18.515±0.00 N/A N/A N/A N/A
ENST00000375429 N/A N/A N/A N/A N/A N/A N/A N/A 2.091±0.00 1.061±0.00 N/A 17.884±10.69 22.984±8.93 N/A
ENST00000441998 29.239±0.00 34.240±0.00 N/A 22.935±0.00 25.690±0.00 20.046±0.00 1.213±0.00 23.280±0.00 N/A N/A N/A 32.805±9.16 16.655±0.76 48.034±5.53
ENST00000444811 14.827±0.00 24.184±0.00 N/A 19.768±0.00 16.634±0.00 15.710±0.00 12.547±0.00 14.249±0.00 5.707±0.00 32.988±0.00 12.816±11.20 25.877±1.63 21.358±1.46 52.634±0.00
ENST00000454913 N/A N/A N/A N/A N/A N/A 5.914±3.60 5.173±0.00 3.968±0.00 N/A N/A 22.190±17.24 27.506±0.00 63.338±25.54
ENST00000481121 N/A N/A 0.885±0.00 3.944±0.00 3.974±0.00 N/A N/A N/A N/A 1.049±0.00 1.992±0.00 N/A N/A 23.445±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003676 IEA nucleic acid binding
GO:0003723 NAS RNA binding
GO:0005515 IPI protein binding
GO:0005634 NAS nucleus
GO:0005654 TAS nucleoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0008150 ND biological_process
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0032021 IDA NELF complex
GO:0034244 IEA negative regulation of transcription elongation from RNA polymerase II promoter
GO:0044822 IDA poly(A) RNA binding
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004343 nelfe negative elongation factor complex member E protein_coding Danio_rerio
ENSMUSG00000024369 Nelfe negative elongation factor complex member E, Rdbp protein_coding Mus_musculus

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