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Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MHC class I polypeptide-related sequence B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204516 MICB 9606 + 6:31494881-31511124 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000252229 MICB-001 31498115-31511124 protein_coding
  ENST00000399150 MICB-002 31498086-31511124 protein_coding
  ENST00000494577 MICB-003 31505935-31507531 retained_intron
  ENST00000538442 MICB-201 31494881-31511123 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000252229ENST00000399150ENST00000494577ENST00000538442
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000252229 0.597±0.00 N/A N/A N/A N/A 0.609±0.00 N/A 0.323±0.00 N/A N/A N/A 2.128±0.54 1.256±1.04 0.751±0.00
ENST00000399150 N/A N/A N/A N/A N/A N/A 0.138±0.00 N/A N/A N/A 0.158±0.03 0.592±0.09 N/A N/A
ENST00000494577 N/A N/A 0.166±0.00 0.195±0.00 0.868±0.07 0.905±0.06 0.093±0.00 0.872±0.71 N/A 0.720±0.00 N/A 1.481±0.73 N/A 0.459±0.00
ENST00000538442 0.383±0.00 1.659±0.00 N/A 0.106±0.00 0.482±0.00 0.633±0.00 0.268±0.00 N/A 0.394±0.29 2.365±0.00 N/A 0.541±0.26 0.638±0.05 0.455±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001FP CIL_0001FP_0004 CGP 6:31399784-31511124

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002429 IDA immune response-activating cell surface receptor signaling pathway
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006955 IEA immune response
GO:0006979 IDA response to oxidative stress
GO:0009408 IDA response to heat
GO:0009986 ISS cell surface
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0019835 IEA cytolysis
GO:0019882 IEA antigen processing and presentation
GO:0032526 IDA response to retinoic acid
GO:0046629 IDA gamma-delta T cell activation
GO:0046703 IDA natural killer cell lectin-like receptor binding
GO:0050689 IDA negative regulation of defense response to virus by host
GO:0050776 TAS regulation of immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001470 mhc1zea major histocompatibility complex class I ZEA protein_coding Danio_rerio
ENSDARG00000036588 mhc1zba major histocompatibility complex class I ZBA protein_coding Danio_rerio
ENSDARG00000069471 mhc1zca major histocompatibility complex class I ZCA protein_coding Danio_rerio
ENSDARG00000074765 mhc1zaa major histocompatibility complex class I ZAA protein_coding Danio_rerio
ENSDARG00000076734 DARE-ZE*0601 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000088022 mhc1zfa major histocompatibility complex class I ZFA protein_coding Danio_rerio
ENSDARG00000092162 mhc1zaa major histocompatibility complex class I ZAA protein_coding Danio_rerio
ENSMUSG00000040987 Mill2 MHC I like leukocyte 2 protein_coding Mus_musculus
ENSMUSG00000054005 Mill1 MHC I like leukocyte 1 protein_coding Mus_musculus

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