C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 1, catalytic subunit, beta isozyme
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213639 PPP1CB 9606 + 2:28751640-28802940 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296122 PPP1CB-003 28751814-28801648 protein_coding
  ENST00000358506 PPP1CB-201 28751748-28802930 protein_coding
  ENST00000395366 PPP1CB-001 28751853-28802940 protein_coding
  ENST00000418910 PPP1CB-009 28779000-28781978 protein_coding
  ENST00000420282 PPP1CB-006 28751676-28778999 protein_coding
  ENST00000427786 PPP1CB-008 28751746-28778931 nonsense_mediated_decay
  ENST00000441461 PPP1CB-005 28751739-28779039 protein_coding
  ENST00000455580 PPP1CB-004 28751640-28783978 protein_coding
  ENST00000464273 PPP1CB-007 28752011-28777261 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296122ENST00000358506ENST00000395366
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296122 34.901±0.00 11.961±0.00 9.889±0.00 29.893±5.89 30.808±0.10 45.878±6.78 34.456±1.83 27.574±12.46 37.531±30.03 36.456±2.12 59.227±43.69 34.554±14.45 19.557±15.35 39.490±9.60
ENST00000358506 N/A N/A N/A 9.199±0.00 N/A N/A N/A 5.505±0.50 3.302±0.00 10.245±0.00 N/A 22.782±0.00 6.443±0.48 N/A
ENST00000395366 22.762±0.00 22.206±0.00 3.975±0.00 18.586±0.00 18.547±13.22 19.934±9.52 17.015±8.31 17.011±0.00 16.882±14.36 13.238±5.54 29.851±18.47 11.791±6.60 3.659±1.55 26.774±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00013Q CIL_00013Q_0001 CGP 2:28457145-28802940

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000164 IEA protein phosphatase type 1 complex
GO:0000278 TAS mitotic cell cycle
GO:0004721 IEA phosphoprotein phosphatase activity
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005925 IDA focal adhesion
GO:0005977 IEA glycogen metabolic process
GO:0005979 IEA regulation of glycogen biosynthetic process
GO:0005981 IEA regulation of glycogen catabolic process
GO:0006470 ISS protein dephosphorylation
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008152 IEA metabolic process
GO:0016787 IEA hydrolase activity
GO:0016791 ISS phosphatase activity
GO:0017018 ISS myosin phosphatase activity
GO:0019433 TAS triglyceride catabolic process
GO:0019901 IPI protein kinase binding
GO:0030155 IDA regulation of cell adhesion
GO:0030512 TAS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032922 ISS circadian regulation of gene expression
GO:0042587 IEA glycogen granule
GO:0042752 IMP regulation of circadian rhythm
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0050115 IDA myosin-light-chain-phosphatase activity
GO:0051301 IEA cell division
GO:0070062 IDA extracellular vesicular exosome
GO:0070688 IDA MLL5-L complex
GO:0072357 IDA PTW/PP1 phosphatase complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044153 ppp1cb protein phosphatase 1, catalytic subunit, beta isoform protein_coding Danio_rerio
ENSMUSG00000014956 Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform protein_coding Mus_musculus

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