C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thioredoxin domain containing 5 (endoplasmic reticulum)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000239264 TXNDC5 9606 - 6:7881517-7910814 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000379757 TXNDC5-001 7881517-7910814 protein_coding
  ENST00000460138 TXNDC5-002 7881517-7889445 retained_intron
  ENST00000469459 TXNDC5-004 7895155-7900242 retained_intron
  ENST00000473453 TXNDC5-003 7883144-7910077 protein_coding
  ENST00000475802 TXNDC5-005 7883155-7888961 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000379757ENST00000473453
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000379757 45.619±0.00 174.138±0.00 5.603±0.00 12.222±0.00 60.889±10.43 45.169±0.03 12.500±7.60 40.277±19.56 52.243±39.73 42.713±22.36 4.033±1.07 74.273±33.53 100.669±8.45 26.702±15.65
ENST00000473453 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 58.687±0.00 71.186±0.00 15.040±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000161 CIL_000161_0002 CGP 6:7726797-8064364
CIL_00015W CIL_00015W_0002 CGP 6:7881517-8064414

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003756 IBA protein disulfide isomerase activity
GO:0005515 IPI protein binding
GO:0005783 IBA endoplasmic reticulum
GO:0005788 IEA endoplasmic reticulum lumen
GO:0006457 IBA protein folding
GO:0006892 TAS post-Golgi vesicle-mediated transport
GO:0016853 IEA isomerase activity
GO:0034976 IBA response to endoplasmic reticulum stress
GO:0043066 TAS negative regulation of apoptotic process
GO:0043202 TAS lysosomal lumen
GO:0043277 IBA apoptotic cell clearance
GO:0045454 IEA cell redox homeostasis
GO:0061024 TAS membrane organization
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009342 txndc5 thioredoxin domain containing 5 protein_coding Danio_rerio
ENSMUSG00000038991 Txndc5 thioredoxin domain containing 5 protein_coding Mus_musculus

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