C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-like with PHD and ring finger domains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000276043 UHRF1 9606 + 19:4903080-4962154 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000612630 UHRF1-006 4903080-4962154 protein_coding
  ENST00000613817 UHRF1-002 4909498-4961171 protein_coding
  ENST00000615884 UHRF1-005 4910146-4960961 protein_coding
  ENST00000616255 UHRF1-004 4910375-4960952 protein_coding
  ENST00000620565 UHRF1-001 4909430-4962150 protein_coding
  ENST00000622802 UHRF1-003 4910367-4961132 protein_coding
  ENST00000624301 UHRF1-201 4909498-4962151 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000612630ENST00000613817ENST00000615884ENST00000616255ENST00000622802ENST00000624301
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000612630 0.317±0.00 0.809±0.00 0.717±0.00 0.496±0.00 0.315±0.00 0.159±0.00 0.180±0.00 0.069±0.00 0.110±0.00 0.036±0.00 0.188±0.00 0.714±0.00 1.760±0.00
ENST00000613817 N/A N/A N/A N/A N/A N/A N/A N/A 0.088±0.00 N/A N/A N/A N/A
ENST00000615884 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.038±0.00 N/A N/A N/A
ENST00000616255 N/A N/A N/A N/A N/A N/A N/A N/A 0.167±0.00 N/A N/A N/A N/A
ENST00000622802 N/A N/A N/A N/A N/A 0.047±0.03 N/A 0.023±0.00 0.098±0.00 N/A N/A N/A 1.165±0.00
ENST00000624301 N/A N/A 0.342±0.24 1.086±0.00 1.040±0.00 0.093±0.03 N/A 0.055±0.00 0.110±0.06 N/A 4.539±2.93 1.614±0.62 2.523±1.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00029M CIL_00029M_0001 CGP 19:4890437-4962154
CIL_0005GV CIL_0005GV_0002 CGP 19:4903080-5153595

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 ISS nuclear chromatin
GO:0000791 IDA euchromatin
GO:0000792 IDA heterochromatin
GO:0000987 IDA core promoter proximal region sequence-specific DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005657 IDA replication fork
GO:0005720 IEA nuclear heterochromatin
GO:0006281 IEA DNA repair
GO:0006351 IEA transcription, DNA-templated
GO:0007049 IEA cell cycle
GO:0008270 IDA:IEA zinc ion binding
GO:0008283 IEP cell proliferation
GO:0008327 IDA methyl-CpG binding
GO:0010216 IMP maintenance of DNA methylation
GO:0010390 ISS histone monoubiquitination
GO:0016363 ISS nuclear matrix
GO:0016574 IDA histone ubiquitination
GO:0016874 IEA ligase activity
GO:0031493 ISS nucleosomal histone binding
GO:0032270 IDA positive regulation of cellular protein metabolic process
GO:0035064 IDA methylated histone binding
GO:0042393 IDA:IEA histone binding
GO:0042787 IDA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0042802 ISS identical protein binding
GO:0044729 IDA hemi-methylated DNA-binding
GO:0045944 IC positive regulation of transcription from RNA polymerase II promoter
GO:0051865 IDA protein autoubiquitination
GO:2000373 IC positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009946 uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 protein_coding Danio_rerio
ENSDARG00000091448 uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 protein_coding Danio_rerio
ENSMUSG00000001228 Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 protein_coding Mus_musculus

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