C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, beta type, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000277791 PSMB3 9606 + 17:38752736-38764231 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000610434 PSMB3-006 38752747-38760580 protein_coding
  ENST00000613870 PSMB3-002 38752764-38764225 nonsense_mediated_decay
  ENST00000614132 PSMB3-005 38760385-38764225 retained_intron
  ENST00000618159 PSMB3-004 38762051-38764225 retained_intron
  ENST00000619426 PSMB3-001 38752736-38764231 protein_coding
  ENST00000620309 PSMB3-003 38752773-38764225 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000610434ENST00000613870ENST00000614132ENST00000619426ENST00000620309
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000610434 23.384±0.00 30.064±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000613870 N/A N/A N/A N/A 1.468±0.00 N/A 6.782±0.00 N/A N/A N/A 7.838±0.00 7.679±0.00 N/A N/A
ENST00000614132 N/A N/A N/A N/A N/A N/A 13.297±0.00 N/A 43.400±0.00 30.663±0.00 N/A N/A N/A N/A
ENST00000619426 56.476±0.00 100.693±0.00 1.757±0.00 37.750±17.16 34.604±32.32 29.841±22.36 25.813±14.42 58.285±36.43 43.176±33.80 49.818±35.75 64.361±53.26 74.347±32.83 116.562±48.72 44.000±20.39
ENST00000620309 N/A N/A N/A N/A 4.201±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005QW CIL_0005QW_0001 CGP 17:38733897-38764231
CIL_0000SI CIL_0000SI_0001 CGP 17:38752736-38800126

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005839 IEA proteasome core complex
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0015629 IDA actin cytoskeleton
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013938 psmb3 proteasome (prosome, macropain) subunit, beta type, 3 protein_coding Danio_rerio
ENSMUSG00000069379 Gm4950 predicted pseudogene 4950 protein_coding Mus_musculus
ENSMUSG00000069744 Psmb3 proteasome (prosome, macropain) subunit, beta type 3 protein_coding Mus_musculus

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