C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: activin A receptor, type 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000532 Acvr1b 10090 + 15:101174067-101213679 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000544 Acvr1b-001 101174067-101213679 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000544
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000544 11.152±0.77 7.034±0.68 12.089±3.32 17.772±5.53 15.092±2.29 44.126±5.76 6.666±0.64 16.706±3.46 4.117±1.12 29.758±0.21 15.002±5.33 12.750±4.50 5.815±1.59 7.082±2.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JY CIL_0006JY_0002 CGP 15:101128522-101213679
CIL_0006JZ CIL_0006JZ_0002 CGP 15:101174067-101232755

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0001701 IMP in utero embryonic development
GO:0001942 IMP hair follicle development
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004675 TAS transmembrane receptor protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0007166 TAS cell surface receptor signaling pathway
GO:0007417 IEA central nervous system development
GO:0007498 ISA mesoderm development
GO:0009966 IDA regulation of signal transduction
GO:0009986 IEA cell surface
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0010862 IEA positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0017002 IEA activin-activated receptor activity
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0019838 IEA growth factor binding
GO:0030308 IEA negative regulation of cell growth
GO:0032924 IDA activin receptor signaling pathway
GO:0032927 IEA positive regulation of activin receptor signaling pathway
GO:0034711 IEA inhibin binding
GO:0038092 IEA nodal signaling pathway
GO:0045648 IEA positive regulation of erythrocyte differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IEA SMAD binding
GO:0046545 IEA development of primary female sexual characteristics
GO:0046777 IEA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048185 IPI activin binding
GO:0070062 IEA extracellular vesicular exosome
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:1901165 IEA positive regulation of trophoblast cell migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018968 acvr1b activin A receptor, type IB protein_coding Danio_rerio
ENSDARG00000052142 ACVR1B (2 of 2) activin A receptor, type IB protein_coding Danio_rerio
ENSG00000135503 ACVR1B activin A receptor, type IB protein_coding Homo_sapiens

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