C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: trans-acting transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001280 Sp1 10090 + 15:102406143-102436404 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001326 Sp1-001 102406380-102436404 protein_coding
  ENSMUST00000163709 Sp1-008 102406333-102432679 protein_coding
  ENSMUST00000165837 Sp1-003 102406755-102408617 protein_coding
  ENSMUST00000165924 Sp1-005 102406328-102432679 protein_coding
  ENSMUST00000168802 Sp1-004 102407588-102408385 protein_coding
  ENSMUST00000169619 Sp1-007 102407269-102408235 protein_coding
  ENSMUST00000170042 Sp1-006 102429899-102430819 processed_transcript
  ENSMUST00000170884 Sp1-002 102406143-102408235 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001326ENSMUST00000163709ENSMUST00000165924
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001326 8.501±3.78 4.669±0.51 7.785±2.33 4.969±2.98 8.403±0.89 5.216±1.22 3.998±1.16 7.815±1.09 6.355±2.73 12.201±2.43 2.250±0.38 9.014±3.15 8.447±4.51 3.630±1.84
ENSMUST00000163709 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.978±0.00 2.640±1.24 0.591±0.00
ENSMUST00000165924 6.545±3.35 11.197±1.36 N/A N/A 10.872±2.56 13.339±0.43 1.096±0.10 4.616±0.13 2.560±0.42 3.648±1.10 N/A 17.161±2.49 N/A 3.055±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00060O CIL_00060O_0002 CGP 15:102356609-102436404
CIL_0009B4 CIL_0009B4_0002 VISTA 15:102394217-102994945
CIL_0001W1 CIL_0001W1_0002 CGP 15:102406143-102454630

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 IDA core promoter proximal region sequence-specific DNA binding
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0001503 IGI ossification
GO:0001701 IGI in utero embryonic development
GO:0001829 IGI trophectodermal cell differentiation
GO:0001889 IGI liver development
GO:0001892 IGI embryonic placenta development
GO:0003677 IDA DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0008022 IEA protein C-terminus binding
GO:0008134 IEA transcription factor binding
GO:0030219 IGI megakaryocyte differentiation
GO:0030324 IGI lung development
GO:0032993 IEA protein-DNA complex
GO:0035035 IEA histone acetyltransferase binding
GO:0035326 IDA enhancer binding
GO:0042803 IEA protein homodimerization activity
GO:0042826 IEA histone deacetylase binding
GO:0043353 IGI enucleate erythrocyte differentiation
GO:0043425 IPI bHLH transcription factor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0043923 IEA positive regulation by host of viral transcription
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045893 ISO positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048511 IEA rhythmic process
GO:0048596 IGI embryonic camera-type eye morphogenesis
GO:0048706 IGI embryonic skeletal system development
GO:0060136 IGI embryonic process involved in female pregnancy
GO:0060216 IGI definitive hemopoiesis
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088347 sp1 sp1 transcription factor protein_coding Danio_rerio
ENSG00000185591 SP1 Sp1 transcription factor protein_coding Homo_sapiens

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