C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myocyte enhancer factor 2D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001419 Mef2d 10090 + 3:88142372-88172086 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001455 Mef2d-001 88142372-88172086 protein_coding
  ENSMUST00000107558 Mef2d-003 88142572-88168655 protein_coding
  ENSMUST00000107559 Mef2d-004 88142572-88168655 protein_coding
  ENSMUST00000119251 Mef2d-002 88142416-88169930 protein_coding
  ENSMUST00000139153 Mef2d-006 88162960-88168785 processed_transcript
  ENSMUST00000140927 Mef2d-005 88142574-88156003 retained_intron
  ENSMUST00000152861 Mef2d-007 88168252-88168906 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001455ENSMUST00000107558ENSMUST00000107559ENSMUST00000119251
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001455 11.453±4.13 22.069±1.08 7.835±4.06 9.722±2.06 17.197±4.67 17.546±3.77 21.365±1.86 6.801±1.78 3.081±1.65 10.662±4.05 26.522±0.00 9.848±6.18 6.330±2.30 1.524±0.20
ENSMUST00000107558 N/A 14.550±0.00 N/A N/A 18.041±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000107559 N/A N/A N/A N/A 13.383±0.00 12.462±0.00 10.976±0.00 N/A 2.328±0.00 11.991±0.43 N/A 13.881±2.78 N/A 2.350±0.00
ENSMUST00000119251 7.578±2.81 21.101±4.32 4.765±0.00 23.800±15.63 11.683±5.51 15.184±2.54 7.979±0.45 5.052±1.03 2.896±1.21 10.740±2.82 13.978±2.46 15.406±6.69 25.441±12.95 1.764±0.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000850 CIL_000850_0002 VISTA 3:87682625-88286876
CIL_0008JO CIL_0008JO_0002 VISTA 3:87838105-88441065

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001649 IGI osteoblast differentiation
GO:0001958 IGI endochondral ossification
GO:0002062 IGI chondrocyte differentiation
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006915 IEA apoptotic process
GO:0007399 IEA nervous system development
GO:0007512 IEA adult heart development
GO:0019899 IPI enzyme binding
GO:0033613 IEA activating transcription factor binding
GO:0035914 IMP skeletal muscle cell differentiation
GO:0042803 IPI protein homodimerization activity
GO:0042826 IEA histone deacetylase binding
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040237 mef2d myocyte enhancer factor 2d protein_coding Danio_rerio
ENSG00000116604 MEF2D myocyte enhancer factor 2D protein_coding Homo_sapiens

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