C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: laminin B1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002900 Lamb1 10090 + 12:31265234-31329644 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002979 Lamb1-001 31265293-31329644 protein_coding
  ENSMUST00000164009 Lamb1-008 31278175-31278939 retained_intron
  ENSMUST00000164228 Lamb1-003 31265294-31268860 retained_intron
  ENSMUST00000164919 Lamb1-005 31265400-31329575 nonsense_mediated_decay
  ENSMUST00000169065 Lamb1-002 31276656-31287986 retained_intron
  ENSMUST00000169088 Lamb1-004 31265234-31329493 protein_coding
  ENSMUST00000170495 Lamb1-006 31265297-31266793 protein_coding
  ENSMUST00000172134 Lamb1-007 31323521-31324454 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002979ENSMUST00000169088
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002979 20.843±6.60 11.247±4.80 23.241±2.22 5.297±3.06 14.308±4.35 5.296±0.65 8.371±2.57 14.166±2.49 1.502±0.80 13.191±6.54 2.136±0.83 22.314±20.51 63.771±33.94 1.123±0.29
ENSMUST00000169088 6.994±0.00 10.561±1.76 N/A 9.819±0.00 9.187±3.90 4.837±0.37 1.413±0.00 3.364±0.76 0.361±0.06 5.220±0.36 N/A 27.169±30.71 150.888±47.51 1.363±1.62

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZV CIL_0008ZV_0002 VISTA 12:31009963-31611477

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005178 IMP integrin binding
GO:0005201 ISS extracellular matrix structural constituent
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005578 IDA proteinaceous extracellular matrix
GO:0005604 IDA:ISS basement membrane
GO:0005605 IDA basal lamina
GO:0005606 IDA:ISS laminin-1 complex
GO:0005607 ISS laminin-2 complex
GO:0005615 IEA extracellular space
GO:0007155 IEA cell adhesion
GO:0007162 IDA negative regulation of cell adhesion
GO:0007566 IMP embryo implantation
GO:0007611 NAS learning or memory
GO:0016477 IMP cell migration
GO:0019899 IPI enzyme binding
GO:0021812 IEA neuronal-glial interaction involved in cerebral cortex radial glia guided migration
GO:0030335 ISS positive regulation of cell migration
GO:0031012 IEA extracellular matrix
GO:0031175 IDA:ISS neuron projection development
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0035987 IEA endodermal cell differentiation
GO:0042476 ISS odontogenesis
GO:0043208 IDA glycosphingolipid binding
GO:0043256 IDA laminin complex
GO:0043257 ISS laminin-8 complex
GO:0043259 IPI:ISS laminin-10 complex
GO:0048471 IDA perinuclear region of cytoplasm
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026491 lamb1a laminin, beta 1a protein_coding Danio_rerio
ENSDARG00000045524 lamb1b laminin, beta 1b protein_coding Danio_rerio
ENSDARG00000089288 lamb1a laminin, beta 1a protein_coding Danio_rerio
ENSG00000091136 LAMB1 laminin, beta 1 protein_coding Homo_sapiens

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