C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: laminin, beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000091136 LAMB1 9606 - 7:107923799-108003255 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222399 LAMB1-001 107923818-108003255 protein_coding
  ENST00000393559 LAMB1-006 107998431-108003160 protein_coding
  ENST00000393560 LAMB1-002 107959506-108003187 protein_coding
  ENST00000393561 LAMB1-003 107923803-108002027 protein_coding
  ENST00000439976 LAMB1-005 107998413-108003176 protein_coding
  ENST00000468518 LAMB1-013 107931357-107932624 processed_transcript
  ENST00000468999 LAMB1-009 107937090-107940564 processed_transcript
  ENST00000470995 LAMB1-010 107935374-107937163 processed_transcript
  ENST00000472714 LAMB1-004 107923799-107929977 retained_intron
  ENST00000474380 LAMB1-012 107929449-107937159 processed_transcript
  ENST00000476039 LAMB1-008 107942399-107953649 processed_transcript
  ENST00000479448 LAMB1-007 107951101-107952090 processed_transcript
  ENST00000491196 LAMB1-011 107935356-107937170 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222399ENST00000393560ENST00000393561
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222399 48.991±0.00 10.883±0.00 N/A N/A 9.543±1.41 21.707±15.29 20.407±0.00 34.241±0.00 6.405±2.68 17.852±13.09 2.999±0.00 15.869±7.27 48.386±12.35 25.754±0.00
ENST00000393560 N/A N/A 10.063±0.00 N/A N/A N/A 5.066±0.00 N/A N/A 6.626±0.00 N/A N/A N/A N/A
ENST00000393561 N/A N/A 8.327±0.00 1.717±0.00 N/A 5.468±0.00 2.522±0.00 N/A 4.107±0.00 3.038±0.00 1.943±0.00 10.707±0.00 38.680±0.00 4.797±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZV CIL_0008ZV_0001 VISTA 7:107646717-108248447
CIL_00063H CIL_00063H_0002 CGP 7:107923799-108130356

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005178 IEA integrin binding
GO:0005198 NAS structural molecule activity
GO:0005201 IDA extracellular matrix structural constituent
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005604 IDA basement membrane
GO:0005605 IEA basal lamina
GO:0005606 IPI laminin-1 complex
GO:0005607 TAS laminin-2 complex
GO:0005615 IDA extracellular space
GO:0007155 TAS cell adhesion
GO:0007162 IEA negative regulation of cell adhesion
GO:0007411 TAS axon guidance
GO:0007566 IEA embryo implantation
GO:0016020 IEA membrane
GO:0016192 IEA vesicle-mediated transport
GO:0016477 IEA cell migration
GO:0019899 IEA enzyme binding
GO:0021812 IMP neuronal-glial interaction involved in cerebral cortex radial glia guided migration
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030335 IDA positive regulation of cell migration
GO:0031012 IDA extracellular matrix
GO:0031175 IDA neuron projection development
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0035987 IEP endodermal cell differentiation
GO:0042476 IDA odontogenesis
GO:0043208 IEA glycosphingolipid binding
GO:0043256 IEA laminin complex
GO:0043257 TAS laminin-8 complex
GO:0043259 IDA laminin-10 complex
GO:0048471 ISS perinuclear region of cytoplasm
GO:0050679 TAS positive regulation of epithelial cell proliferation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026491 lamb1a laminin, beta 1a protein_coding Danio_rerio
ENSDARG00000045524 lamb1b laminin, beta 1b protein_coding Danio_rerio
ENSDARG00000089288 lamb1a laminin, beta 1a protein_coding Danio_rerio
ENSMUSG00000002900 Lamb1 laminin B1 protein_coding Mus_musculus

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