C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sterile alpha motif and leucine zipper containing kinase AZK
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004085 Zak 10090 + 2:72285637-72442610 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000090824 Zak-001 72285637-72442610 protein_coding
  ENSMUST00000112073 Zak-003 72285764-72399237 retained_intron
  ENSMUST00000135204 Zak-005 72285794-72364843 retained_intron
  ENSMUST00000135469 Zak-002 72285728-72407502 protein_coding
  ENSMUST00000144111 Zak-006 72297901-72355622 protein_coding
  ENSMUST00000150126 Zak-004 72285777-72389839 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000090824ENSMUST00000135469
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000090824 N/A 1.368±0.43 N/A 0.534±0.13 1.572±0.00 1.887±0.11 N/A 1.650±0.03 2.166±0.53 4.175±0.45 N/A 2.415±0.59 0.518±0.11 N/A
ENSMUST00000135469 17.994±2.20 4.057±0.56 26.758±4.13 0.931±0.55 10.599±6.87 8.063±1.40 33.700±7.18 2.292±0.94 2.034±0.63 18.310±1.65 18.624±4.00 9.844±3.95 0.859±0.78 1.382±0.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003IJ CIL_0003IJ_0003 CGP 2:71981240-72442610
CIL_0008JV CIL_0008JV_0002 VISTA 2:72126155-72727698
CIL_0004KE CIL_0004KE_0002 CGP 2:72285637-72486893

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000075 ISS cell cycle checkpoint
GO:0000077 IEA DNA damage checkpoint
GO:0000186 IDA:IEA activation of MAPKK activity
GO:0000287 IDA magnesium ion binding
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004709 IDA MAP kinase kinase kinase activity
GO:0005524 IEA:IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006468 IEA:IDA protein phosphorylation
GO:0007010 IDA cytoskeleton organization
GO:0007050 IEA cell cycle arrest
GO:0007257 IEA activation of JUN kinase activity
GO:0009314 IEA response to radiation
GO:0035556 IDA intracellular signal transduction
GO:0043065 ISS positive regulation of apoptotic process
GO:0044822 IEA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006978 zak sterile alpha motif and leucine zipper containing kinase AZK protein_coding Danio_rerio
ENSDARG00000044615 zak sterile alpha motif and leucine zipper containing kinase AZK protein_coding Danio_rerio
ENSG00000091436 ZAK Mitogen-activated protein kinase kinase kinase MLT protein_coding Homo_sapiens

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