C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sterile alpha motif and leucine zipper containing kinase AZK
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000090824 Zak-001 ENSMUSG00000004085 10090 + 2:72285637-72442610 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonKidneyLiverLungOvaryPlacentaENSMUST00000090824
Transcript ID Adrenal Brain Breast Colon Kidney Liver Lung Ovary Placenta
ENSMUST00000090824 1.368±0.43 0.534±0.13 1.572±0.00 1.887±0.11 1.650±0.03 2.166±0.53 4.175±0.45 2.415±0.59 0.518±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003IJ CIL_0003IJ_0003 CGP 2:71981240-72442610
CIL_0008JV CIL_0008JV_0002 VISTA 2:72126155-72727698
CIL_0004KE CIL_0004KE_0002 CGP 2:72285637-72486893

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000075 ISS cell cycle checkpoint
GO:0000077 IEA DNA damage checkpoint
GO:0000186 IDA:IEA activation of MAPKK activity
GO:0000287 IDA magnesium ion binding
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004709 IDA MAP kinase kinase kinase activity
GO:0005524 IEA:IDA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006468 IEA:IDA protein phosphorylation
GO:0007010 IDA cytoskeleton organization
GO:0007050 IEA cell cycle arrest
GO:0007257 IEA activation of JUN kinase activity
GO:0009314 IEA response to radiation
GO:0035556 IDA intracellular signal transduction
GO:0043065 ISS positive regulation of apoptotic process
GO:0044822 IEA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000338983 ZAK-002 protein_coding Homo_sapiens 0 1546
ENST00000375213 ZAK-001 protein_coding Homo_sapiens 0 2830
ENST00000409176 ZAK-003 protein_coding Homo_sapiens 0 2806
ENST00000422149 ZAK-006 protein_coding Homo_sapiens 0 656
ENST00000468408 ZAK-005 processed_transcript Homo_sapiens 0 599
ENST00000476618 ZAK-004 retained_intron Homo_sapiens 0 1380
ENST00000480606 ZAK-007 processed_transcript Homo_sapiens 0 608
ENST00000539448 ZAK-201 protein_coding Homo_sapiens 0 1519

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