C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DNA methyltransferase (cytosine-5) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004099 Dnmt1 10090 - 9:20907206-20959888 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004202 Dnmt1-201 20907206-20952979 protein_coding
  ENSMUST00000177754 Dnmt1-202 20907206-20959888 protein_coding
  ENSMUST00000178110 Dnmt1-203 20907206-20952623 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004202ENSMUST00000177754ENSMUST00000178110
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004202 1.678±1.00 2.911±0.97 4.562±0.12 14.149±2.01 2.342±0.31 2.492±0.70 1.460±0.48 1.610±0.45 11.665±9.73 2.843±0.93 0.926±0.46 15.113±15.58 25.041±14.26 2.166±1.33
ENSMUST00000177754 4.307±3.93 8.542±3.55 2.065±0.41 5.310±1.73 4.171±2.59 5.959±2.64 0.702±0.00 2.099±0.94 6.638±4.52 5.820±1.53 0.444±0.08 12.179±5.97 6.446±2.16 2.722±0.64
ENSMUST00000178110 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.307±1.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004BQ CIL_0004BQ_0003 CGP 9:20894352-20959888
CIL_000773 CIL_000773_0003 CGP 9:20907206-20976793

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000792 IDA heterochromatin
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003723 IDA RNA binding
GO:0003886 IDA DNA (cytosine-5-)-methyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005657 IDA replication fork
GO:0005721 IDA pericentric heterochromatin
GO:0005737 IEA cytoplasm
GO:0006306 IDA DNA methylation
GO:0006351 IEA transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0008168 IDA methyltransferase activity
GO:0008270 IDA zinc ion binding
GO:0008327 IDA methyl-CpG binding
GO:0009008 IEA DNA-methyltransferase activity
GO:0010216 IMP maintenance of DNA methylation
GO:0010468 IMP regulation of gene expression
GO:0010628 IEA positive regulation of gene expression
GO:0016458 IDA gene silencing
GO:0016568 IEA chromatin modification
GO:0042127 IGI regulation of cell proliferation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0051571 IEA positive regulation of histone H3-K4 methylation
GO:0051573 IEA negative regulation of histone H3-K9 methylation
GO:0071230 IDA cellular response to amino acid stimulus
GO:0090116 IEA C-5 methylation of cytosine

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030756 dnmt1 DNA (cytosine-5-)-methyltransferase 1 protein_coding Danio_rerio
ENSG00000130816 DNMT1 DNA (cytosine-5-)-methyltransferase 1 protein_coding Homo_sapiens

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