C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DNA methyltransferase (cytosine-5) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000004202 Dnmt1-201 ENSMUSG00000004099 10090 - 9:20907206-20952979 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004202
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004202 1.678±1.00 2.911±0.97 4.562±0.12 14.149±2.01 2.342±0.31 2.492±0.70 1.460±0.48 1.610±0.45 11.665±9.73 2.843±0.93 0.926±0.46 15.113±15.58 25.041±14.26 2.166±1.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004BQ CIL_0004BQ_0003 CGP 9:20894352-20959888
CIL_000773 CIL_000773_0003 CGP 9:20907206-20976793

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000792 IDA heterochromatin
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003723 IDA RNA binding
GO:0003886 IDA DNA (cytosine-5-)-methyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005657 IDA replication fork
GO:0005721 IDA pericentric heterochromatin
GO:0005737 IEA cytoplasm
GO:0006306 IDA DNA methylation
GO:0006351 IEA transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0008168 IDA methyltransferase activity
GO:0008270 IDA zinc ion binding
GO:0008327 IDA methyl-CpG binding
GO:0009008 IEA DNA-methyltransferase activity
GO:0010216 IMP maintenance of DNA methylation
GO:0010468 IMP regulation of gene expression
GO:0010628 IEA positive regulation of gene expression
GO:0016458 IDA gene silencing
GO:0016568 IEA chromatin modification
GO:0042127 IGI regulation of cell proliferation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0051571 IEA positive regulation of histone H3-K4 methylation
GO:0051573 IEA negative regulation of histone H3-K9 methylation
GO:0071230 IDA cellular response to amino acid stimulus
GO:0090116 IEA C-5 methylation of cytosine

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000021977 dnmt1-001 protein_coding Danio_rerio 0 979
ENSDART00000078973 dnmt1-201 protein_coding Danio_rerio 0 970
ENST00000340748 DNMT1-001 protein_coding Homo_sapiens 0 3103
ENST00000359526 DNMT1-002 protein_coding Homo_sapiens 0 3103
ENST00000540357 DNMT1-201 protein_coding Homo_sapiens 0 3103
ENST00000586588 DNMT1-004 retained_intron Homo_sapiens 0 1882
ENST00000586667 DNMT1-020 retained_intron Homo_sapiens 0 411
ENST00000586799 DNMT1-019 nonsense_mediated_decay Homo_sapiens 0 459
ENST00000588913 DNMT1-008 nonsense_mediated_decay Homo_sapiens 0 1096
ENST00000589351 DNMT1-024 retained_intron Homo_sapiens 0 281
ENST00000592705 DNMT1-006 nonsense_mediated_decay Homo_sapiens 0 3103
ENST00000593049 DNMT1-021 processed_transcript Homo_sapiens 0 396

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