C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peroxiredoxin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005161 Prdx2 10090 + 8:84969587-84974834 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005292 Prdx2-001 84969611-84974834 protein_coding
  ENSMUST00000109733 Prdx2-005 84969767-84974834 protein_coding
  ENSMUST00000109734 Prdx2-003 84969587-84974834 protein_coding
  ENSMUST00000125893 Prdx2-006 84969857-84971621 protein_coding
  ENSMUST00000127215 Prdx2-007 84971456-84974311 retained_intron
  ENSMUST00000138748 Prdx2-004 84969694-84971125 retained_intron
  ENSMUST00000143402 Prdx2-002 84969694-84972103 retained_intron
  ENSMUST00000164807 Prdx2-201 84970239-84974660 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000005292ENSMUST00000109734ENSMUST00000125893ENSMUST00000127215ENSMUST00000143402ENSMUST00000164807
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000005292 98.489±17.95 114.048±23.77 116.718±0.00 231.770±4.04 67.238±25.23 85.323±10.44 125.653±26.61 113.160±17.34 160.406±188.84 64.144±7.19 34.022±11.78 126.054±50.81 42.514±46.23
ENSMUST00000109734 N/A N/A N/A 43.011±0.00 N/A N/A N/A N/A 111.654±45.54 N/A N/A N/A N/A
ENSMUST00000125893 N/A N/A N/A 39.074±0.00 N/A N/A N/A N/A N/A N/A N/A 50.344±0.00 20.851±0.00
ENSMUST00000127215 N/A N/A N/A N/A N/A N/A N/A N/A 531.703±74.59 N/A 26.630±0.00 N/A 93.943±35.63
ENSMUST00000143402 N/A N/A N/A N/A N/A N/A 64.821±4.47 N/A 172.654±78.20 24.567±0.00 N/A N/A 41.273±0.00
ENSMUST00000164807 N/A 97.605±15.13 70.736±0.00 17.151±0.00 44.950±0.00 N/A N/A N/A 152.057±0.00 N/A 32.081±8.54 114.590±66.88 40.098±35.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZV CIL_0007ZV_0002 VISTA 8:84428902-85032705
CIL_0007VV CIL_0007VV_0002 VISTA 8:84441926-85045230
CIL_00063Y CIL_00063Y_0002 CGP 8:84956610-84974834
CIL_000640 CIL_000640_0002 CGP 8:84969587-84978748

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IMP activation of MAPK activity
GO:0002536 IMP respiratory burst involved in inflammatory response
GO:0004601 TAS peroxidase activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0006979 TAS response to oxidative stress
GO:0008379 ISS thioredoxin peroxidase activity
GO:0008430 TAS selenium binding
GO:0010310 IMP regulation of hydrogen peroxide metabolic process
GO:0019430 IMP removal of superoxide radicals
GO:0030194 IMP positive regulation of blood coagulation
GO:0031665 IMP negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032088 IMP negative regulation of NF-kappaB transcription factor activity
GO:0032496 IMP response to lipopolysaccharide
GO:0042098 IMP T cell proliferation
GO:0042743 IMP hydrogen peroxide metabolic process
GO:0042744 IMP hydrogen peroxide catabolic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045581 IMP negative regulation of T cell differentiation
GO:0048538 IMP thymus development
GO:0048872 IMP homeostasis of number of cells
GO:0055114 IEA oxidation-reduction process
GO:2000378 IMP negative regulation of reactive oxygen species metabolic process
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway
GO:2001240 IDA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025350 prdx2 peroxiredoxin 2 protein_coding Danio_rerio
ENSG00000167815 PRDX2 peroxiredoxin 2 protein_coding Homo_sapiens

Loading