C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor receptor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005320 Fgfr4 10090 + 13:55152640-55168759 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005452 Fgfr4-001 55152640-55168759 protein_coding
  ENSMUST00000162167 Fgfr4-003 55156117-55156904 retained_intron
  ENSMUST00000162967 Fgfr4-002 55155683-55156655 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005452ENSMUST00000162167ENSMUST00000162967
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005452 0.064±0.07 4.781±1.70 0.030±0.00 0.206±0.18 0.239±0.01 7.016±1.27 0.067±0.01 9.722±3.66 6.552±4.25 14.984±3.01 0.355±0.11 1.019±0.35 3.118±2.18 0.210±0.07
ENSMUST00000162167 0.160±0.10 N/A 0.187±0.00 0.104±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000162967 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.547±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A2 CIL_0008A2_0002 VISTA 13:55104361-55707564
CIL_0000OQ CIL_0000OQ_0003 CGP 13:55152640-55318325

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001759 IMP organ induction
GO:0005007 ISS fibroblast growth factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005783 ISS endoplasmic reticulum
GO:0005887 ISS integral component of plasma membrane
GO:0005911 ISS cell-cell junction
GO:0008201 ISS heparin binding
GO:0008284 ISS positive regulation of cell proliferation
GO:0008543 ISS fibroblast growth factor receptor signaling pathway
GO:0010715 ISS regulation of extracellular matrix disassembly
GO:0016477 ISS cell migration
GO:0017134 ISS fibroblast growth factor binding
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0019216 IMP regulation of lipid metabolic process
GO:0030324 IMP lung development
GO:0042593 IMP glucose homeostasis
GO:0045862 ISS positive regulation of proteolysis
GO:0046777 ISS protein autophosphorylation
GO:0048554 ISS positive regulation of metalloenzyme activity
GO:0055062 IMP phosphate ion homeostasis
GO:0061144 IGI alveolar secondary septum development
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070857 IMP regulation of bile acid biosynthetic process
GO:2000188 IMP regulation of cholesterol homeostasis
GO:2000573 ISS positive regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069105 fgfr4 fibroblast growth factor receptor 4 protein_coding Danio_rerio
ENSG00000160867 FGFR4 fibroblast growth factor receptor 4 protein_coding Homo_sapiens

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