C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor receptor 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000005452 Fgfr4-001 ENSMUSG00000005320 10090 + 13:55152640-55168759 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005452
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005452 0.064±0.07 4.781±1.70 0.030±0.00 0.206±0.18 0.239±0.01 7.016±1.27 0.067±0.01 9.722±3.66 6.552±4.25 14.984±3.01 0.355±0.11 1.019±0.35 3.118±2.18 0.210±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A2 CIL_0008A2_0002 VISTA 13:55104361-55707564
CIL_0000OQ CIL_0000OQ_0003 CGP 13:55152640-55318325

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001759 IMP organ induction
GO:0005007 ISS fibroblast growth factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005768 IEA endosome
GO:0005783 ISS endoplasmic reticulum
GO:0005887 ISS integral component of plasma membrane
GO:0005911 ISS cell-cell junction
GO:0008201 ISS heparin binding
GO:0008284 ISS positive regulation of cell proliferation
GO:0008543 ISS fibroblast growth factor receptor signaling pathway
GO:0010715 ISS regulation of extracellular matrix disassembly
GO:0016477 ISS cell migration
GO:0017134 ISS fibroblast growth factor binding
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0019216 IMP regulation of lipid metabolic process
GO:0030324 IMP lung development
GO:0042593 IMP glucose homeostasis
GO:0045862 ISS positive regulation of proteolysis
GO:0046777 ISS protein autophosphorylation
GO:0048554 ISS positive regulation of metalloenzyme activity
GO:0055062 IMP phosphate ion homeostasis
GO:0061144 IGI alveolar secondary septum development
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070857 IMP regulation of bile acid biosynthetic process
GO:2000188 IMP regulation of cholesterol homeostasis
GO:2000573 ISS positive regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000260795 FGFR3-001 protein_coding Homo_sapiens 0 276
ENST00000292408 FGFR4-001 protein_coding Homo_sapiens 0 2521
ENST00000340107 FGFR3-201 protein_coding Homo_sapiens 0 276
ENST00000352904 FGFR3-002 protein_coding Homo_sapiens 0 276
ENST00000393637 FGFR4-002 protein_coding Homo_sapiens 0 1319
ENST00000393648 FGFR4-003 protein_coding Homo_sapiens 0 1179
ENST00000412135 FGFR3-202 protein_coding Homo_sapiens 0 276
ENST00000430285 FGFR4-005 nonsense_mediated_decay Homo_sapiens 0 527
ENST00000440486 FGFR3-203 protein_coding Homo_sapiens 0 276
ENST00000474521 FGFR3-004 processed_transcript Homo_sapiens 0 204
ENST00000481110 FGFR3-006 protein_coding Homo_sapiens 0 276
ENST00000502906 FGFR4-004 protein_coding Homo_sapiens 0 2536
ENST00000503708 FGFR4-010 protein_coding Homo_sapiens 0 592
ENST00000507588 FGFR3-007 protein_coding Homo_sapiens 7.00649e-45 183
ENST00000508139 FGFR4-013 retained_intron Homo_sapiens 0 549
ENST00000509511 FGFR4-007 retained_intron Homo_sapiens 0 1105
ENST00000511076 FGFR4-014 protein_coding Homo_sapiens 0 839
ENST00000613647 FGFR3-204 protein_coding Homo_sapiens 0 276

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