C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mutS homolog 6 (E. coli)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005370 Msh6 10090 + 17:87975050-87990883 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005503 Msh6-201 87975050-87990883 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005503
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005503 3.515±1.56 3.208±0.00 4.504±0.32 7.893±0.98 3.647±1.15 3.155±0.39 1.268±0.23 2.438±0.25 5.786±5.53 3.029±0.43 1.308±0.20 9.224±7.12 12.579±9.23 6.346±6.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00066I CIL_00066I_0002 CGP 17:87975050-88065291

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0000400 IBA four-way junction DNA binding
GO:0000710 IBA meiotic mismatch repair
GO:0000790 IDA nuclear chromatin
GO:0003677 IGI DNA binding
GO:0003682 IDA chromatin binding
GO:0003684 IGI damaged DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006200 IBA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006298 IGI mismatch repair
GO:0007131 IBA reciprocal meiotic recombination
GO:0008094 IBA DNA-dependent ATPase activity
GO:0008340 IMP determination of adult lifespan
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411 IMP response to UV
GO:0016446 IMP somatic hypermutation of immunoglobulin genes
GO:0016447 IMP somatic recombination of immunoglobulin gene segments
GO:0016887 IEA ATPase activity
GO:0030983 ISS mismatched DNA binding
GO:0032137 IDA guanine/thymine mispair binding
GO:0032138 IBA single base insertion or deletion binding
GO:0032142 IEA single guanine insertion binding
GO:0032143 IEA single thymine insertion binding
GO:0032301 IDA MutSalpha complex
GO:0032357 IEA oxidized purine DNA binding
GO:0032405 IEA MutLalpha complex binding
GO:0035064 ISS methylated histone binding
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043531 IEA ADP binding
GO:0043570 IBA maintenance of DNA repeat elements
GO:0045190 IMP isotype switching
GO:0045910 IMP negative regulation of DNA recombination
GO:0051096 IEA positive regulation of helicase activity
GO:0097193 IMP intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011666 msh6 mutS homolog 6 (E. coli) protein_coding Danio_rerio
ENSG00000116062 MSH6 mutS homolog 6 protein_coding Homo_sapiens

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