C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mutS homolog 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116062 MSH6 9606 + 2:47695530-47810101 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000234420 MSH6-001 47783082-47810101 protein_coding
  ENST00000411819 MSH6-006 47784181-47798733 protein_coding
  ENST00000420813 MSH6-005 47783955-47796036 protein_coding
  ENST00000445503 MSH6-002 47783082-47806953 nonsense_mediated_decay
  ENST00000454137 MSH6-010 47695816-47757793 processed_transcript
  ENST00000455383 MSH6-004 47783585-47798627 protein_coding
  ENST00000456246 MSH6-003 47783128-47798920 nonsense_mediated_decay
  ENST00000493177 MSH6-007 47783170-47784976 processed_transcript
  ENST00000538136 MSH6-201 47783955-47806945 protein_coding
  ENST00000540021 MSH6-202 47783082-47806945 protein_coding
  ENST00000606499 MSH6-008 47695819-47791116 protein_coding
  ENST00000607272 MSH6-009 47695530-47709833 processed_transcript
  ENST00000614496 MSH6-203 47783082-47806945 protein_coding
  ENST00000616033 MSH6-204 47783151-47801332 protein_coding
  ENST00000622629 MSH6-205 47783082-47806952 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000234420ENST00000538136ENST00000540021ENST00000622629
Transcript ID Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000234420 N/A 0.873±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000538136 N/A N/A N/A N/A N/A N/A N/A N/A 3.675±0.00 N/A N/A N/A
ENST00000540021 8.153±0.00 N/A 9.611±0.00 7.195±0.00 1.095±0.00 6.729±0.00 4.039±1.20 4.488±0.00 N/A 18.854±3.86 8.087±6.11 26.414±5.24
ENST00000622629 N/A 1.687±0.00 N/A N/A 2.308±1.34 N/A N/A 3.944±0.17 N/A 12.672±0.00 7.207±4.84 22.320±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00066I CIL_00066I_0001 CGP 2:47695530-47905793

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000228 IBA nuclear chromosome
GO:0000287 IDA magnesium ion binding
GO:0000400 IDA four-way junction DNA binding
GO:0000710 ISS meiotic mismatch repair
GO:0000790 IEA nuclear chromatin
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003684 IEA damaged DNA binding
GO:0003690 IDA double-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006200 IBA ATP catabolic process
GO:0006281 IDA DNA repair
GO:0006298 IDA:IEA mismatch repair
GO:0007131 IBA reciprocal meiotic recombination
GO:0008094 IBA DNA-dependent ATPase activity
GO:0008340 ISS determination of adult lifespan
GO:0008630 ISS intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411 ISS response to UV
GO:0016446 ISS somatic hypermutation of immunoglobulin genes
GO:0016447 ISS somatic recombination of immunoglobulin gene segments
GO:0016887 IDA ATPase activity
GO:0030983 IDA:IEA mismatched DNA binding
GO:0032137 IDA guanine/thymine mispair binding
GO:0032142 IDA single guanine insertion binding
GO:0032143 IDA single thymine insertion binding
GO:0032301 IDA MutSalpha complex
GO:0032357 IDA oxidized purine DNA binding
GO:0032405 IDA MutLalpha complex binding
GO:0035064 IDA methylated histone binding
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043531 IDA ADP binding
GO:0045190 ISS isotype switching
GO:0045910 IDA negative regulation of DNA recombination
GO:0051096 IDA positive regulation of helicase activity
GO:0097193 ISS intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011666 msh6 mutS homolog 6 (E. coli) protein_coding Danio_rerio
ENSMUSG00000005370 Msh6 mutS homolog 6 (E. coli) protein_coding Mus_musculus

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