C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HtrA serine peptidase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006205 Htra1 10090 + 7:130936111-130985660 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006367 Htra1-001 130936203-130985660 protein_coding
  ENSMUST00000140741 Htra1-004 130981670-130982443 retained_intron
  ENSMUST00000150717 Htra1-003 130936111-130979934 retained_intron
  ENSMUST00000150905 Htra1-005 130982730-130985396 processed_transcript
  ENSMUST00000153290 Htra1-002 130943489-130985660 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006367ENSMUST00000150717ENSMUST00000150905ENSMUST00000153290
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006367 76.193±7.36 14.467±1.95 70.584±8.84 7.507±5.62 67.202±1.56 23.391±1.60 28.247±6.41 43.405±2.43 0.537±0.35 20.651±2.68 7.379±1.31 218.979±57.10 21.529±21.71 1.812±0.72
ENSMUST00000150717 N/A 32.589±11.10 N/A N/A 56.816±24.95 15.102±2.38 N/A 7.300±0.00 0.444±0.09 10.632±3.74 N/A 115.158±24.97 N/A 0.349±0.00
ENSMUST00000150905 N/A N/A N/A N/A N/A N/A N/A N/A 0.365±0.22 N/A N/A N/A 1.901±0.00 1.775±0.50
ENSMUST00000153290 N/A N/A N/A 50.702±0.00 83.262±0.00 N/A 4.513±0.00 N/A 0.177±0.16 N/A 4.205±1.32 217.613±21.04 46.282±20.40 1.326±0.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002WI CIL_0002WI_0002 CGP 7:129591863-133123350
CIL_0001BE CIL_0001BE_0002 CGP 7:130162451-133123350
CIL_0005TA CIL_0005TA_0002 CGP 7:130865756-130985660
CIL_0000QM CIL_0000QM_0002 CGP 7:130936111-131121626

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005737 IEA cytoplasm
GO:0006508 IDA proteolysis
GO:0008236 IDA serine-type peptidase activity
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0031012 IEA extracellular matrix
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0050687 IEA negative regulation of defense response to virus
GO:0070062 IEA extracellular vesicular exosome
GO:0097187 IEA dentinogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014907 htra1b HtrA serine peptidase 1b protein_coding Danio_rerio
ENSDARG00000032831 htra1a HtrA serine peptidase 1a protein_coding Danio_rerio
ENSG00000166033 HTRA1 HtrA serine peptidase 1 protein_coding Homo_sapiens

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