C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: actin related protein 2/3 complex, subunit 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006304 Arpc2 10090 + 1:74236084-74268209 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006467 Arpc2-002 74236517-74267987 protein_coding
  ENSMUST00000113819 Arpc2-003 74236550-74267988 protein_coding
  ENSMUST00000113820 Arpc2-001 74236497-74268209 protein_coding
  ENSMUST00000185733 Arpc2-004 74236084-74236888 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006467ENSMUST00000113819ENSMUST00000113820
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006467 60.409±11.24 77.738±16.86 72.657±14.40 46.398±7.78 102.778±54.90 119.721±24.70 17.822±4.96 38.551±11.63 29.220±20.83 96.204±17.65 12.480±3.03 87.634±21.46 89.619±17.19 13.212±3.82
ENSMUST00000113819 10.301±0.00 N/A N/A N/A 68.309±55.56 N/A 9.291±1.53 N/A N/A N/A N/A N/A N/A 14.462±2.91
ENSMUST00000113820 13.204±1.61 24.209±0.00 43.893±18.32 29.814±10.04 11.151±0.00 20.411±1.76 19.206±4.12 18.542±7.77 31.833±13.01 16.151±0.00 19.123±6.33 60.964±44.91 67.193±38.36 30.643±12.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WL CIL_0007WL_0002 VISTA 1:73730234-74332407
CIL_0005VM CIL_0005VM_0002 CGP 1:74191785-74268209
CIL_0005VL CIL_0005VL_0002 CGP 1:74236084-74279624

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0005200 IEA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005768 IDA endosome
GO:0005794 IEA Golgi apparatus
GO:0005885 TAS Arp2/3 protein complex
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0010592 IEA positive regulation of lamellipodium assembly
GO:0019894 IEA kinesin binding
GO:0030838 IDA positive regulation of actin filament polymerization
GO:0031252 IDA cell leading edge
GO:0035650 IEA AP-1 adaptor complex binding
GO:0043005 IEA neuron projection
GO:0045202 IEA synapse
GO:0051015 IEA actin filament binding
GO:0070062 IEA extracellular vesicular exosome
GO:0071933 IEA Arp2/3 complex binding
GO:1900026 IMP positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075989 arpc2 actin related protein 2/3 complex, subunit 2 protein_coding Danio_rerio
ENSG00000163466 ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa protein_coding Homo_sapiens

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