C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000007097 Atp1a2 10090 - 1:172271709-172298064 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085913 Atp1a2-001 172271709-172298064 protein_coding
  ENSMUST00000097464 Atp1a2-004 172278083-172298064 protein_coding
  ENSMUST00000131751 Atp1a2-003 172274543-172298064 retained_intron
  ENSMUST00000137679 Atp1a2-002 172284309-172298064 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENSMUST00000085913ENSMUST00000097464ENSMUST00000131751
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENSMUST00000085913 85.882±50.64 17.471±4.00 6.478±0.27 23.850±24.14 77.742±30.88 4.233±0.48 72.246±11.17 6.197±1.05 16.674±4.92 46.417±40.40 10.117±3.74 1.873±0.00 4.701±1.50
ENSMUST00000097464 54.729±25.08 22.827±5.99 8.736±0.07 67.275±58.77 54.885±25.98 4.643±0.00 54.089±6.32 6.048±0.97 13.440±3.09 114.605±26.48 12.484±2.73 2.748±0.00 2.060±0.00
ENSMUST00000131751 21.271±0.98 12.636±2.09 N/A 24.149±21.03 21.240±6.88 N/A 23.458±0.00 3.636±0.20 10.713±0.81 76.882±22.28 10.795±3.99 N/A 3.191±0.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005I6 CIL_0005I6_0002 CGP 1:172261641-172319841

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001504 IMP neurotransmitter uptake
GO:0002026 IMP regulation of the force of heart contraction
GO:0002087 IMP regulation of respiratory gaseous exchange by neurological system process
GO:0005391 ISS sodium:potassium-exchanging ATPase activity
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005768 IEA endosome
GO:0005886 ISS plasma membrane
GO:0005890 IEA sodium:potassium-exchanging ATPase complex
GO:0005901 IEA caveola
GO:0006754 IEA ATP biosynthetic process
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006883 IEA cellular sodium ion homeostasis
GO:0006937 IMP regulation of muscle contraction
GO:0006940 IMP regulation of smooth muscle contraction
GO:0006942 IMP regulation of striated muscle contraction
GO:0008217 IGI regulation of blood pressure
GO:0008344 IMP adult locomotory behavior
GO:0008542 IMP visual learning
GO:0010107 IEA potassium ion import
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0019229 IGI regulation of vasoconstriction
GO:0030007 IEA cellular potassium ion homeostasis
GO:0030315 IDA T-tubule
GO:0031982 IEA vesicle
GO:0035094 IEA response to nicotine
GO:0035725 IEA sodium ion transmembrane transport
GO:0036376 IEA sodium ion export from cell
GO:0040011 IMP locomotion
GO:0042383 IDA sarcolemma
GO:0043005 IEA neuron projection
GO:0043197 IEA dendritic spine
GO:0045202 IEA synapse
GO:0045822 IMP negative regulation of heart contraction
GO:0045988 IMP negative regulation of striated muscle contraction
GO:0046872 IEA metal ion binding
GO:0051087 IEA chaperone binding
GO:0051481 IMP negative regulation of cytosolic calcium ion concentration
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071383 IDA cellular response to steroid hormone stimulus
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:1903416 IMP response to glycoside
GO:1990239 IEA steroid hormone binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010472 atp1a2a ATPase, Na+/K+ transporting, alpha 2a polypeptide protein_coding Danio_rerio
ENSG00000018625 ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide protein_coding Homo_sapiens

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