C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Na+/K+ transporting, alpha 2 polypeptide
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000085913 Atp1a2-001 ENSMUSG00000007097 10090 - 1:172271709-172298064 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENSMUST00000085913
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENSMUST00000085913 85.882±50.64 17.471±4.00 6.478±0.27 23.850±24.14 77.742±30.88 4.233±0.48 72.246±11.17 6.197±1.05 16.674±4.92 46.417±40.40 10.117±3.74 1.873±0.00 4.701±1.50

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005I6 CIL_0005I6_0002 CGP 1:172261641-172319841

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001504 IMP neurotransmitter uptake
GO:0002026 IMP regulation of the force of heart contraction
GO:0002087 IMP regulation of respiratory gaseous exchange by neurological system process
GO:0005391 ISS sodium:potassium-exchanging ATPase activity
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005768 IEA endosome
GO:0005886 ISS plasma membrane
GO:0005890 IEA sodium:potassium-exchanging ATPase complex
GO:0005901 IEA caveola
GO:0006754 IEA ATP biosynthetic process
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006883 IEA cellular sodium ion homeostasis
GO:0006937 IMP regulation of muscle contraction
GO:0006940 IMP regulation of smooth muscle contraction
GO:0006942 IMP regulation of striated muscle contraction
GO:0008217 IGI regulation of blood pressure
GO:0008344 IMP adult locomotory behavior
GO:0008542 IMP visual learning
GO:0010107 IEA potassium ion import
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0019229 IGI regulation of vasoconstriction
GO:0030007 IEA cellular potassium ion homeostasis
GO:0030315 IDA T-tubule
GO:0031982 IEA vesicle
GO:0035094 IEA response to nicotine
GO:0035725 IEA sodium ion transmembrane transport
GO:0036376 IEA sodium ion export from cell
GO:0040011 IMP locomotion
GO:0042383 IDA sarcolemma
GO:0043005 IEA neuron projection
GO:0043197 IEA dendritic spine
GO:0045202 IEA synapse
GO:0045822 IMP negative regulation of heart contraction
GO:0045988 IMP negative regulation of striated muscle contraction
GO:0046872 IEA metal ion binding
GO:0051087 IEA chaperone binding
GO:0051481 IMP negative regulation of cytosolic calcium ion concentration
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071383 IDA cellular response to steroid hormone stimulus
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:1903416 IMP response to glycoside
GO:1990239 IEA steroid hormone binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000104950 atp1a3a-001 protein_coding Danio_rerio 0 1941
ENSDART00000093298 atp1a2a-201 protein_coding Danio_rerio 0 1829
ENSDART00000011188 atp1a2a-001 protein_coding Danio_rerio 0 1829
ENSDART00000124130 atp1a3b-201 protein_coding Danio_rerio 0 1655
ENSDART00000149975 atp1a3b-001 protein_coding Danio_rerio 0 1655
ENSDART00000081047 atp1a1a.1-001 protein_coding Danio_rerio 0 1607
ENSDART00000006013 atp1a1a.5-001 protein_coding Danio_rerio 0 1005
ENSDART00000149502 atp1a3b-003 retained_intron Danio_rerio 0 381
ENSDART00000137184 atp1a1a.1-005 processed_transcript Danio_rerio 0 259
ENST00000262623 ATP4A-001 protein_coding Homo_sapiens 0 623
ENST00000302102 ATP1A3-001 protein_coding Homo_sapiens 0 2444
ENST00000361216 ATP1A2-001 protein_coding Homo_sapiens 0 4148
ENST00000368081 ATP1A4-001 protein_coding Homo_sapiens 0 1954
ENST00000392233 ATP1A2-003 protein_coding Homo_sapiens 0 3960
ENST00000418334 ATP1A4-002 processed_transcript Homo_sapiens 0 1003
ENST00000441343 ATP1A3-002 non_stop_decay Homo_sapiens 0 2401
ENST00000447527 ATP1A2-008 protein_coding Homo_sapiens 0 2274
ENST00000463989 ATP1A2-005 retained_intron Homo_sapiens 0 492
ENST00000468587 ATP1A2-006 retained_intron Homo_sapiens 0 475
ENST00000469023 ATP1A4-003 retained_intron Homo_sapiens 0 1107
ENST00000472488 ATP1A2-002 retained_intron Homo_sapiens 0 3856
ENST00000477338 ATP1A4-004 nonsense_mediated_decay Homo_sapiens 0 1495
ENST00000478587 ATP1A2-007 retained_intron Homo_sapiens 4e-19 99
ENST00000543770 ATP1A3-007 protein_coding Homo_sapiens 0 2444
ENST00000545399 ATP1A3-008 protein_coding Homo_sapiens 0 2444
ENST00000592131 ATP4A-002 retained_intron Homo_sapiens 0 211
ENST00000602133 ATP1A3-005 protein_coding Homo_sapiens 0 2444

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