C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: bone morphogenetic protein 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000008999 Bmp7 10090 - 2:172868012-172940321 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000009143 Bmp7-001 172868012-172940321 protein_coding
  ENSMUST00000137247 Bmp7-002 172916118-172940092 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000009143ENSMUST00000137247
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000009143 8.649±8.45 27.973±5.32 14.639±0.61 5.970±3.59 3.184±1.31 8.524±0.68 0.567±0.22 18.459±1.83 0.908±0.57 1.625±0.29 0.136±0.03 7.807±3.55 1.569±1.20 0.576±0.38
ENSMUST00000137247 0.145±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.236±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000339 CIL_000339_0002 CGP 2:172549593-172940321
CIL_0008YW CIL_0008YW_0002 VISTA 2:172561962-173164167
CIL_0008TD CIL_0008TD_0002 VISTA 2:172564603-173165839
CIL_0008HJ CIL_0008HJ_0002 VISTA 2:172734798-173336840
CIL_0008BA CIL_0008BA_0002 VISTA 2:172748983-173356071
CIL_0006IN CIL_0006IN_0003 CGP 2:172868012-172993576

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001654 IMP eye development
GO:0001656 IEA metanephros development
GO:0001657 IMP ureteric bud development
GO:0001707 IGI mesoderm formation
GO:0001822 IMP kidney development
GO:0001823 IEA mesonephros development
GO:0005125 TAS cytokine activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0007389 IMP pattern specification process
GO:0007411 IDA axon guidance
GO:0007435 IMP salivary gland morphogenesis
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009880 IMP embryonic pattern specification
GO:0009887 IMP organ morphogenesis
GO:0010800 IEA positive regulation of peptidyl-threonine phosphorylation
GO:0010862 ISS positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010942 IGI positive regulation of cell death
GO:0030326 IGI embryonic limb morphogenesis
GO:0030501 IEA positive regulation of bone mineralization
GO:0030509 IDA BMP signaling pathway
GO:0030855 IMP epithelial cell differentiation
GO:0031012 IEA extracellular matrix
GO:0031988 IEA membrane-bounded vesicle
GO:0032355 IEA response to estradiol
GO:0033280 IEA response to vitamin D
GO:0034116 IEA positive regulation of heterotypic cell-cell adhesion
GO:0034504 ISS protein localization to nucleus
GO:0035239 IDA tube morphogenesis
GO:0040007 IEA growth
GO:0042325 IEA regulation of phosphorylation
GO:0042326 ISS negative regulation of phosphorylation
GO:0042475 IDA odontogenesis of dentin-containing tooth
GO:0043065 IMP positive regulation of apoptotic process
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0043434 IEA response to peptide hormone
GO:0045597 IDA positive regulation of cell differentiation
GO:0045665 IMP negative regulation of neuron differentiation
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045746 IGI negative regulation of Notch signaling pathway
GO:0045786 IEA negative regulation of cell cycle
GO:0045839 ISS negative regulation of mitosis
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048468 IDA cell development
GO:0048593 IMP camera-type eye morphogenesis
GO:0048596 IMP embryonic camera-type eye morphogenesis
GO:0048646 IMP anatomical structure formation involved in morphogenesis
GO:0048754 IDA branching morphogenesis of an epithelial tube
GO:0048762 ISS mesenchymal cell differentiation
GO:0048812 IMP neuron projection morphogenesis
GO:0050768 IDA negative regulation of neurogenesis
GO:0051216 IEA cartilage development
GO:0060272 IGI embryonic skeletal joint morphogenesis
GO:0060393 IEA regulation of pathway-restricted SMAD protein phosphorylation
GO:0060395 ISS SMAD protein signal transduction
GO:0060445 IMP branching involved in salivary gland morphogenesis
GO:0060485 IMP mesenchyme development
GO:0060548 IEA negative regulation of cell death
GO:0060686 IDA negative regulation of prostatic bud formation
GO:0060687 IMP regulation of branching involved in prostate gland morphogenesis
GO:0070487 IEA monocyte aggregation
GO:0070700 ISO BMP receptor binding
GO:0072040 IMP negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
GO:0072125 ISS negative regulation of glomerular mesangial cell proliferation
GO:0072133 IGI metanephric mesenchyme morphogenesis
GO:0072134 IGI nephrogenic mesenchyme morphogenesis
GO:0072136 IGI metanephric mesenchymal cell proliferation involved in metanephros development
GO:1900006 IEA positive regulation of dendrite development
GO:1900106 IEA positive regulation of hyaluranon cable assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018260 bmp7a bone morphogenetic protein 7a protein_coding Danio_rerio
ENSDARG00000063230 bmp7b bone morphogenetic protein 7b protein_coding Danio_rerio
ENSG00000101144 BMP7 bone morphogenetic protein 7 protein_coding Homo_sapiens

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