C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000010797 Wnt2 10090 - 6:17988940-18030585 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000010941 Wnt2-001 17988940-18030585 protein_coding
  ENSMUST00000156317 Wnt2-002 17989215-18030410 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000010941ENSMUST00000156317
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000010941 1.297±0.22 0.261±0.12 7.197±1.05 0.274±0.28 5.128±2.32 0.276±0.14 0.313±0.13 0.182±0.07 0.700±0.40 7.307±0.79 0.068±0.01 0.234±0.14 0.800±0.36 0.468±0.38
ENSMUST00000156317 0.355±0.00 0.249±0.16 12.554±1.38 0.686±0.57 2.007±0.76 0.322±0.07 0.152±0.04 0.129±0.05 0.620±0.35 2.903±1.28 0.062±0.02 0.256±0.21 1.219±0.61 0.441±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003QW CIL_0003QW_0002 CGP 6:17692933-18030585
CIL_00063S CIL_00063S_0003 CGP 6:17988940-18109061

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0002053 IMP positive regulation of mesenchymal cell proliferation
GO:0005109 IBA frizzled binding
GO:0005125 IEA cytokine activity
GO:0005515 IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IBA extracellular space
GO:0005737 ISO cytoplasm
GO:0005886 IEA plasma membrane
GO:0007267 IEA cell-cell signaling
GO:0008284 IEA positive regulation of cell proliferation
GO:0016055 IGI Wnt signaling pathway
GO:0030182 IBA neuron differentiation
GO:0030324 IEA lung development
GO:0031012 IEA extracellular matrix
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0055009 IMP atrial cardiac muscle tissue morphogenesis
GO:0060045 IMP positive regulation of cardiac muscle cell proliferation
GO:0060070 IGI canonical Wnt signaling pathway
GO:0060317 IMP cardiac epithelial to mesenchymal transition
GO:0060492 IGI lung induction
GO:0060501 IMP positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060716 IMP labyrinthine layer blood vessel development
GO:0061180 IEA mammary gland epithelium development
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:0090263 IEA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041117 wnt2 wingless-type MMTV integration site family member 2 protein_coding Danio_rerio
ENSG00000105989 WNT2 wingless-type MMTV integration site family member 2 protein_coding Homo_sapiens

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