C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Nanog homeobox
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112580 Nanog-002 ENSMUSG00000012396 10090 + 6:122707565-122714633 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainHeartLiverOvaryTestisENSMUST00000112580
Transcript ID Adipose Brain Heart Liver Ovary Testis
ENSMUST00000112580 0.115±0.13 0.047±0.00 0.002±0.00 0.008±0.01 0.008±0.00 0.075±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001C CIL_00001C_0002 CGP 6:122707489-122801640

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001710 IGI mesodermal cell fate commitment
GO:0001714 ISO endodermal cell fate specification
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003714 IMP transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008284 IDA positive regulation of cell proliferation
GO:0008406 IEP gonad development
GO:0009880 IEP embryonic pattern specification
GO:0010033 IDA response to organic substance
GO:0010454 IDA negative regulation of cell fate commitment
GO:0017145 IDA stem cell division
GO:0019827 IMP stem cell maintenance
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0032526 IDA response to retinoic acid
GO:0042664 TAS negative regulation of endodermal cell fate specification
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045596 IDA negative regulation of cell differentiation
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045931 IDA positive regulation of mitotic cell cycle
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048863 IMP stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000229307 NANOG-001 protein_coding Homo_sapiens 0 283
ENST00000424456 NANOGP5-001 transcribed_processed_pseudogene Homo_sapiens 2e-38 163
ENST00000453325 NANOGP10-001 processed_pseudogene Homo_sapiens 0 243
ENST00000525030 NANOGP1-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 281
ENST00000526286 NANOG-002 protein_coding Homo_sapiens 0 226
ENST00000526434 NANOG-003 processed_transcript Homo_sapiens 4e-29 132
ENST00000528386 NANOGP8-001 processed_pseudogene Homo_sapiens 0 294
ENST00000541267 NANOG-004 protein_coding Homo_sapiens 0 267
ENST00000607111 NANOGP1-002 processed_transcript Homo_sapiens 0 211

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