C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014426 Map3k4 10090 - 17:12227621-12318660 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089058 Map3k4-201 12227621-12318660 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089058
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089058 0.936±0.00 1.305±0.07 2.609±0.10 4.219±0.93 1.642±0.69 2.073±0.43 1.571±0.91 1.929±0.61 0.925±0.47 1.105±0.39 1.523±0.77 3.310±1.61 2.194±0.42 1.068±0.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007Y5 CIL_0007Y5_0002 VISTA 17:11903951-12505747
CIL_00031W CIL_00031W_0002 CGP 17:12118704-12318660

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0001890 IMP placenta development
GO:0004672 IDA protein kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0010225 IEA response to UV-C
GO:0010468 IMP regulation of gene expression
GO:0019100 IMP male germ-line sex determination
GO:0035556 IDA intracellular signal transduction
GO:0043507 IMP positive regulation of JUN kinase activity
GO:0046872 IEA metal ion binding
GO:0048263 ISO determination of dorsal identity
GO:0060718 IMP chorionic trophoblast cell differentiation
GO:1900745 IEA positive regulation of p38MAPK cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053303 map3k4 mitogen activated protein kinase kinase kinase 4 protein_coding Danio_rerio
ENSG00000085511 MAP3K4 mitogen-activated protein kinase kinase kinase 4 protein_coding Homo_sapiens

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