C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: piezo-type mechanosensitive ion channel component 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014444 Piezo1 10090 - 8:122481698-122551329 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067252 Piezo1-201 122481698-122551329 protein_coding
  ENSMUST00000123671 Piezo1-008 122481721-122484780 retained_intron
  ENSMUST00000126553 Piezo1-007 122483367-122483869 retained_intron
  ENSMUST00000128383 Piezo1-001 122481982-122499885 nonsense_mediated_decay
  ENSMUST00000134304 Piezo1-006 122482041-122483000 retained_intron
  ENSMUST00000148497 Piezo1-002 122485924-122498204 nonsense_mediated_decay
  ENSMUST00000152596 Piezo1-004 122484865-122485624 retained_intron
  ENSMUST00000155803 Piezo1-005 122482080-122482676 retained_intron
  ENSMUST00000156333 Piezo1-003 122481712-122499886 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091T CIL_00091T_0002 VISTA 8:122411841-123013825
CIL_0000Y8 CIL_0000Y8_0003 CGP 8:122466147-122484138
CIL_0000Y5 CIL_0000Y5_0003 CGP 8:122476143-122551329
CIL_00057I CIL_00057I_0003 CGP 8:122481698-122573128

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005261 IDA cation channel activity
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0006812 IDA cation transport
GO:0008381 IDA mechanically-gated ion channel activity
GO:0016021 IEA integral component of membrane
GO:0033625 IEA positive regulation of integrin activation
GO:0033634 IEA positive regulation of cell-cell adhesion mediated by integrin
GO:0034220 IDA ion transmembrane transport
GO:0042391 IMP regulation of membrane potential
GO:0050982 IMP detection of mechanical stimulus
GO:0098655 IDA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076870 piezo1 piezo-type mechanosensitive ion channel component 1 protein_coding Danio_rerio
ENSG00000103335 PIEZO1 piezo-type mechanosensitive ion channel component 1 protein_coding Homo_sapiens

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