C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: piezo-type mechanosensitive ion channel component 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103335 PIEZO1 9606 - 16:88715343-88785211 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301015 PIEZO1-001 88715346-88785211 protein_coding
  ENST00000327397 PIEZO1-201 88715491-88717611 protein_coding
  ENST00000419505 PIEZO1-003 88715343-88719890 nonsense_mediated_decay
  ENST00000466823 PIEZO1-017 88717722-88720258 protein_coding
  ENST00000472168 PIEZO1-013 88715816-88716792 retained_intron
  ENST00000474606 PIEZO1-009 88722982-88726344 protein_coding
  ENST00000475586 PIEZO1-008 88723947-88726025 retained_intron
  ENST00000484567 PIEZO1-004 88715343-88718318 retained_intron
  ENST00000490756 PIEZO1-006 88732464-88732980 retained_intron
  ENST00000491917 PIEZO1-007 88727074-88727843 retained_intron
  ENST00000495568 PIEZO1-010 88717023-88720473 retained_intron
  ENST00000497793 PIEZO1-011 88718972-88720387 retained_intron
  ENST00000518793 PIEZO1-015 88715343-88716277 protein_coding
  ENST00000521877 PIEZO1-014 88715449-88716212 retained_intron
  ENST00000566414 PIEZO1-016 88722523-88723934 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301015ENST00000327397ENST00000474606ENST00000484567ENST00000490756
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301015 25.183±0.00 10.758±0.00 1.627±1.09 14.468±11.43 11.601±0.00 2.895±2.56 4.528±3.70 2.528±0.00 6.956±5.90 0.507±0.18 8.330±1.79 20.677±8.81 2.248±0.64
ENST00000327397 N/A N/A N/A N/A 20.394±0.00 N/A 17.577±0.00 5.222±0.00 N/A N/A N/A N/A N/A
ENST00000474606 N/A N/A 3.070±0.00 11.432±0.00 N/A N/A 7.265±0.00 12.387±0.00 8.358±0.00 N/A N/A N/A N/A
ENST00000484567 N/A N/A N/A 3.077±0.00 N/A N/A N/A N/A 2.261±0.00 2.200±0.00 9.461±5.76 N/A 5.112±0.00
ENST00000490756 N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.931±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091T CIL_00091T_0001 VISTA 16:88690989-89294615
CIL_0000Y8 CIL_0000Y8_0002 CGP 16:88696495-88715386
CIL_0000Y5 CIL_0000Y5_0002 CGP 16:88706463-88785211
CIL_00057I CIL_00057I_0002 CGP 16:88715343-88809258

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005261 ISS cation channel activity
GO:0005783 IDA endoplasmic reticulum
GO:0005886 ISS plasma membrane
GO:0006812 ISS cation transport
GO:0008381 IEA mechanically-gated ion channel activity
GO:0016021 IEA integral component of membrane
GO:0033625 IMP positive regulation of integrin activation
GO:0033634 IMP positive regulation of cell-cell adhesion mediated by integrin
GO:0034220 IEA ion transmembrane transport
GO:0042391 IEA regulation of membrane potential
GO:0050982 IEA detection of mechanical stimulus
GO:0098655 ISS cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076870 piezo1 piezo-type mechanosensitive ion channel component 1 protein_coding Danio_rerio
ENSMUSG00000014444 Piezo1 piezo-type mechanosensitive ion channel component 1 protein_coding Mus_musculus

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