C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor, erythroid derived 2, like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015839 Nfe2l2 10090 - 2:75675513-75704641 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000102672 Nfe2l2-001 75675513-75704641 protein_coding
  ENSMUST00000152371 Nfe2l2-002 75691052-75704489 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102672
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102672 27.187±7.68 37.009±1.87 75.799±5.16 4.052±0.35 29.515±5.34 50.956±5.48 17.719±1.10 30.162±3.45 24.965±3.95 46.926±7.86 11.254±0.95 49.103±7.39 22.729±4.11 6.558±1.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00017P CIL_00017P_0002 CGP 2:75659261-75704641
CIL_00017Q CIL_00017Q_0002 CGP 2:75675513-75931350

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000785 IDA chromatin
GO:0000976 IEA transcription regulatory region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001205 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001221 IEA transcription cofactor binding
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IPI cytoplasm
GO:0005813 IEA centrosome
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0010499 ISS proteasomal ubiquitin-independent protein catabolic process
GO:0010628 IEA positive regulation of gene expression
GO:0016567 ISS protein ubiquitination
GO:0019904 IEA protein domain specific binding
GO:0030194 IMP positive regulation of blood coagulation
GO:0030968 IDA endoplasmic reticulum unfolded protein response
GO:0034599 IMP cellular response to oxidative stress
GO:0036003 IEA positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0036091 IEA positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045995 IGI regulation of embryonic development
GO:0060548 IEA negative regulation of cell death
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071499 IEA cellular response to laminar fluid shear stress
GO:1902176 IEA negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1903206 IEA negative regulation of hydrogen peroxide-induced cell death
GO:2000121 IMP regulation of removal of superoxide radicals
GO:2000352 IEA negative regulation of endothelial cell apoptotic process
GO:2000379 IMP positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042824 nfe2l2a nuclear factor (erythroid-derived 2)-like 2a protein_coding Danio_rerio
ENSG00000116044 NFE2L2 nuclear factor, erythroid 2-like 2 protein_coding Homo_sapiens

Loading