C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000016028 Celsr1 10090 - 15:85898758-86033777 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000016172 Celsr1-201 85898758-86033777 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000016172
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000016172 1.675±1.12 0.291±0.10 0.355±0.07 3.517±1.88 1.702±0.93 8.424±0.32 0.751±0.09 1.568±0.50 0.073±0.01 4.359±0.18 0.057±0.07 6.710±1.62 0.782±0.52 0.064±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BF CIL_0008BF_0002 VISTA 15:85812646-86415385
CIL_00024N CIL_00024N_0002 CGP 15:85879312-86033777
CIL_0000V3 CIL_0000V3_0003 CGP 15:85898758-86137634

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001702 NAS gastrulation with mouth forming second
GO:0001736 IMP establishment of planar polarity
GO:0001764 IMP neuron migration
GO:0001843 IMP neural tube closure
GO:0001942 IMP hair follicle development
GO:0004888 NAS transmembrane signaling receptor activity
GO:0004930 NAS G-protein coupled receptor activity
GO:0005509 TAS calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007165 NAS signal transduction
GO:0007186 NAS G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0007266 IMP Rho protein signal transduction
GO:0007267 NAS cell-cell signaling
GO:0007417 NAS central nervous system development
GO:0007626 IMP locomotory behavior
GO:0009952 IMP anterior/posterior pattern specification
GO:0016020 IDA membrane
GO:0032956 IMP regulation of actin cytoskeleton organization
GO:0042060 IGI wound healing
GO:0042249 IMP establishment of planar polarity of embryonic epithelium
GO:0042472 IMP inner ear morphogenesis
GO:0045176 IMP apical protein localization
GO:0046928 NAS regulation of neurotransmitter secretion
GO:0046983 NAS protein dimerization activity
GO:0048105 IMP establishment of body hair planar orientation
GO:0060488 IMP orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis
GO:0060489 IMP planar dichotomous subdivision of terminal units involved in lung branching morphogenesis
GO:0060490 IMP lateral sprouting involved in lung morphogenesis
GO:0090179 IGI planar cell polarity pathway involved in neural tube closure
GO:0090251 IDA protein localization involved in establishment of planar polarity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058259 celsr1b cadherin EGF LAG seven-pass G-type receptor 1b protein_coding Danio_rerio
ENSDARG00000069185 celsr1a cadherin EGF LAG seven-pass G-type receptor 1a protein_coding Danio_rerio
ENSG00000075275 CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 protein_coding Homo_sapiens

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