C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase C, gamma 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000016933 Plcg1 10090 + 2:160731300-160775760 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017077 Plcg1-008 160740987-160762506 processed_transcript
  ENSMUST00000103115 Plcg1-001 160731310-160775760 protein_coding
  ENSMUST00000109462 Plcg1-003 160731733-160763286 protein_coding
  ENSMUST00000124652 Plcg1-007 160754572-160759447 processed_transcript
  ENSMUST00000129568 Plcg1-005 160754547-160755169 retained_intron
  ENSMUST00000143997 Plcg1-002 160760118-160762217 protein_coding
  ENSMUST00000147254 Plcg1-006 160754906-160757147 retained_intron
  ENSMUST00000151590 Plcg1-004 160731300-160762502 nonsense_mediated_decay
  ENSMUST00000173061 Plcg1-012 160754067-160754864 retained_intron
  ENSMUST00000173335 Plcg1-010 160752552-160758907 retained_intron
  ENSMUST00000173791 Plcg1-009 160752487-160762155 retained_intron
  ENSMUST00000174885 Plcg1-011 160731699-160747888 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017077ENSMUST00000103115ENSMUST00000109462ENSMUST00000143997ENSMUST00000151590ENSMUST00000174885
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017077 13.445±0.11 9.305±0.97 N/A 9.117±0.00 10.543±3.95 N/A 5.200±0.51 N/A 3.105±1.98 11.167±2.34 N/A N/A N/A N/A
ENSMUST00000103115 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.805±0.13 N/A N/A
ENSMUST00000109462 13.774±1.08 7.612±1.97 15.803±0.72 27.011±10.92 8.209±2.52 3.782±0.41 8.831±0.76 8.653±1.53 5.716±1.97 18.914±3.47 5.955±0.61 26.469±12.14 20.431±6.97 4.608±0.30
ENSMUST00000143997 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 28.731±0.42 N/A
ENSMUST00000151590 10.434±0.00 11.200±4.19 N/A 15.053±0.00 6.419±0.00 4.349±1.34 N/A 5.092±1.61 3.769±0.09 11.105±1.50 N/A 17.001±4.11 N/A N/A
ENSMUST00000174885 N/A 50.842±15.07 N/A N/A 35.281±3.63 N/A N/A N/A N/A 64.759±0.00 N/A 64.489±6.41 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TO CIL_0008TO_0002 VISTA 2:160151305-160752587
CIL_0009AU CIL_0009AU_0002 VISTA 2:160192291-160794448
CIL_0007XA CIL_0007XA_0002 VISTA 2:160203620-160804635
CIL_0008MI CIL_0008MI_0002 VISTA 2:160213670-160814864
CIL_0008QO CIL_0008QO_0002 VISTA 2:160215694-160817266
CIL_0009AV CIL_0009AV_0002 VISTA 2:160278530-160880585
CIL_0004EC CIL_0004EC_0002 CGP 2:160645888-160775760
CIL_0002I4 CIL_0002I4_0002 CGP 2:160731300-160872998

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001726 ISS ruffle
GO:0004435 IEA phosphatidylinositol phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005168 IEA neurotrophin TRKA receptor binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005737 ISO cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0007173 IEA epidermal growth factor receptor signaling pathway
GO:0008152 IEA metabolic process
GO:0008180 IEA COP9 signalosome
GO:0009395 IEA phospholipid catabolic process
GO:0010634 ISS positive regulation of epithelial cell migration
GO:0016042 IEA lipid catabolic process
GO:0016477 IEA cell migration
GO:0019722 IEA calcium-mediated signaling
GO:0019901 IEA protein kinase binding
GO:0030027 ISS lamellipodium
GO:0030971 IPI receptor tyrosine kinase binding
GO:0035254 IPI glutamate receptor binding
GO:0035556 IEA intracellular signal transduction
GO:0042995 IEA cell projection
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0045766 IEA positive regulation of angiogenesis
GO:0050852 IDA T cell receptor signaling pathway
GO:0051281 IEA positive regulation of release of sequestered calcium ion into cytosol
GO:0071364 ISS cellular response to epidermal growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088094 plcb4 phospholipase C, beta 4 protein_coding Danio_rerio
ENSG00000124181 PLCG1 phospholipase C, gamma 1 protein_coding Homo_sapiens

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