C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TNF receptor associated factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017386 Traf4 10090 - 11:78158499-78165589 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017530 Traf4-001 78159400-78165589 protein_coding
  ENSMUST00000148218 Traf4-003 78160793-78165516 retained_intron
  ENSMUST00000149437 Traf4-002 78158499-78165589 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017530ENSMUST00000148218ENSMUST00000149437
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017530 9.662±7.14 32.674±3.32 10.639±2.06 43.140±44.48 8.093±3.39 36.725±17.15 4.056±0.92 30.445±14.77 21.141±7.89 9.018±4.98 1.203±0.32 25.784±16.03 16.481±5.92 3.253±1.23
ENSMUST00000148218 N/A 32.844±9.69 N/A N/A N/A 18.795±4.22 N/A 15.935±0.00 13.463±2.27 7.847±0.00 N/A 16.725±3.70 5.577±0.00 N/A
ENSMUST00000149437 N/A N/A N/A 0.152±0.00 N/A N/A N/A N/A N/A N/A 0.227±0.06 2.545±0.24 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005923 IEA tight junction
GO:0006915 IEA apoptotic process
GO:0007250 IEA activation of NF-kappaB-inducing kinase activity
GO:0007585 IMP respiratory gaseous exchange
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0019901 IPI protein kinase binding
GO:0030323 IMP respiratory tube development
GO:0031625 IEA ubiquitin protein ligase binding
GO:0031996 IEA thioesterase binding
GO:0042981 IEA regulation of apoptotic process
GO:0045860 ISS positive regulation of protein kinase activity
GO:0046330 ISS positive regulation of JNK cascade
GO:0050699 IEA WW domain binding
GO:0090073 IEA positive regulation of protein homodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003963 traf4a tnf receptor-associated factor 4a protein_coding Danio_rerio
ENSG00000076604 TRAF4 TNF receptor-associated factor 4 protein_coding Homo_sapiens

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