C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TNF receptor-associated factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000076604 TRAF4 9606 + 17:28743984-28750958 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262395 TRAF4-001 28743984-28750958 protein_coding
  ENST00000262396 TRAF4-010 28744085-28749644 protein_coding
  ENST00000394925 TRAF4-006 28744055-28747713 retained_intron
  ENST00000422344 TRAF4-002 28744030-28748326 protein_coding
  ENST00000444415 TRAF4-009 28744040-28750037 protein_coding
  ENST00000454852 TRAF4-019 28747214-28749023 nonsense_mediated_decay
  ENST00000461195 TRAF4-008 28744019-28748423 retained_intron
  ENST00000469529 TRAF4-007 28747730-28749034 retained_intron
  ENST00000473421 TRAF4-004 28747016-28748423 protein_coding
  ENST00000475329 TRAF4-003 28744223-28748326 nonsense_mediated_decay
  ENST00000478021 TRAF4-005 28744018-28745518 nonsense_mediated_decay
  ENST00000498540 TRAF4-014 28744023-28747732 retained_intron
  ENST00000578917 TRAF4-017 28747582-28748153 retained_intron
  ENST00000580073 TRAF4-018 28748124-28748742 retained_intron
  ENST00000584944 TRAF4-016 28746743-28748297 protein_coding
  ENST00000586813 TRAF4-020 28744036-28748603 nonsense_mediated_decay
  ENST00000618771 TRAF4-201 28744005-28749577 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262395ENST00000262396ENST00000422344ENST00000444415ENST00000454852ENST00000461195ENST00000469529ENST00000580073ENST00000584944ENST00000586813ENST00000618771
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262395 N/A N/A 0.588±0.00 N/A N/A N/A 0.103±0.01 4.746±0.00 2.380±2.03 0.312±0.00 0.142±0.00 9.026±1.98 7.346±3.19 4.881±0.00
ENST00000262396 N/A N/A N/A N/A N/A N/A N/A N/A 0.539±0.00 N/A N/A 2.593±0.00 N/A N/A
ENST00000422344 N/A N/A N/A N/A N/A N/A 0.157±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000444415 0.535±0.00 3.359±0.00 N/A N/A 1.322±0.00 2.359±0.24 0.318±0.00 7.384±0.00 4.262±0.00 11.314±0.00 0.428±0.00 12.616±0.00 11.722±5.89 5.809±3.22
ENST00000454852 N/A N/A 1.532±0.00 N/A N/A N/A 0.404±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000461195 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.144±0.00 N/A N/A
ENST00000469529 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.452±0.00 N/A N/A N/A N/A
ENST00000580073 N/A N/A N/A N/A N/A 3.077±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000584944 N/A N/A N/A 1.945±0.00 2.595±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000586813 N/A N/A N/A N/A N/A N/A N/A 2.005±0.00 0.663±0.00 N/A N/A N/A N/A N/A
ENST00000618771 2.662±0.00 13.292±0.00 N/A N/A 16.226±0.00 6.339±0.00 N/A 27.515±0.00 9.882±9.03 29.307±0.00 N/A N/A 10.297±0.00 7.551±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004ZR CIL_0004ZR_0002 CGP 17:28725897-28750958

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 TAS DNA binding
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005164 IPI tumor necrosis factor receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005923 IEA tight junction
GO:0006915 IEA apoptotic process
GO:0007165 TAS:IEA signal transduction
GO:0007250 IEA activation of NF-kappaB-inducing kinase activity
GO:0007585 IEA respiratory gaseous exchange
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0019901 IEA protein kinase binding
GO:0030323 IEA respiratory tube development
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031996 IPI thioesterase binding
GO:0042981 IEA regulation of apoptotic process
GO:0045860 IDA positive regulation of protein kinase activity
GO:0046330 IEA:IDA positive regulation of JNK cascade
GO:0046872 IEA metal ion binding
GO:0050699 IPI WW domain binding
GO:0090073 IDA positive regulation of protein homodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003963 traf4a tnf receptor-associated factor 4a protein_coding Danio_rerio
ENSMUSG00000017386 Traf4 TNF receptor associated factor 4 protein_coding Mus_musculus

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