C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: suppressor of zeste 12 homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017548 Suz12 10090 + 11:79993106-80034123 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017692 Suz12-001 79993106-80034123 protein_coding
  ENSMUST00000126091 Suz12-002 79995791-80013587 nonsense_mediated_decay
  ENSMUST00000132312 Suz12-005 79995586-79999564 retained_intron
  ENSMUST00000144188 Suz12-003 80025195-80032001 nonsense_mediated_decay
  ENSMUST00000148140 Suz12-004 79995617-80013657 retained_intron
  ENSMUST00000163272 Suz12-201 79993106-80034122 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017692ENSMUST00000144188ENSMUST00000163272
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017692 3.834±2.37 2.307±0.62 7.623±0.13 7.268±3.78 2.518±1.54 2.556±0.51 1.877±0.91 2.693±0.95 13.800±8.48 4.453±1.19 2.942±0.58 4.861±2.71 15.928±1.71 2.868±1.29
ENSMUST00000144188 N/A N/A N/A 12.369±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 55.164±24.65 N/A
ENSMUST00000163272 1.593±0.66 N/A 1.639±0.15 5.379±2.13 0.928±0.25 N/A 1.016±0.63 2.756±0.89 3.406±1.35 2.757±0.00 0.506±0.07 5.781±5.86 11.682±10.15 1.822±0.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VR CIL_0000VR_0002 CGP 11:79932321-80034123

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001739 IDA sex chromatin
GO:0003682 IDA chromatin binding
GO:0003723 IPI RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008284 IMP positive regulation of cell proliferation
GO:0016571 IMP histone methylation
GO:0016574 IMP histone ubiquitination
GO:0035064 IEA methylated histone binding
GO:0035098 IDA ESC/E(Z) complex
GO:0042054 IEA histone methyltransferase activity
GO:0043565 IDA sequence-specific DNA binding
GO:0045596 IEA negative regulation of cell differentiation
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052022 suz12b suppressor of zeste 12 homolog (Drosophila) b protein_coding Danio_rerio
ENSDARG00000070256 suz12a suppressor of zeste 12 homolog (Drosophila) a protein_coding Danio_rerio
ENSG00000178691 SUZ12 SUZ12 polycomb repressive complex 2 subunit protein_coding Homo_sapiens

Loading