C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SUZ12 polycomb repressive complex 2 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178691 SUZ12 9606 + 17:31937018-32001045 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322652 SUZ12-001 31937018-32001045 protein_coding
  ENST00000494429 SUZ12-003 31965695-31967589 retained_intron
  ENST00000578106 SUZ12-004 31994353-31999376 retained_intron
  ENST00000580398 SUZ12-002 31937067-32000649 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000322652ENST00000494429ENST00000578106ENST00000580398
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000322652 3.239±0.00 2.222±0.00 1.235±0.00 2.440±0.71 2.962±0.00 4.196±0.00 1.668±0.96 3.693±0.93 1.866±0.07 5.248±0.00 1.882±0.00 3.720±0.94 2.836±0.53 6.683±2.55
ENST00000494429 N/A N/A N/A N/A 1.492±0.00 1.312±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000578106 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.779±0.00 6.424±0.00 18.813±0.00
ENST00000580398 1.312±0.00 N/A 0.422±0.00 0.275±0.00 1.440±0.00 1.616±0.00 0.464±0.19 N/A 1.353±0.00 N/A 0.324±0.00 4.618±2.78 7.233±0.00 13.766±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VR CIL_0000VR_0001 CGP 17:31860899-32001045

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001739 IEA sex chromatin
GO:0003682 IEA chromatin binding
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008284 IEA positive regulation of cell proliferation
GO:0016571 IEA histone methylation
GO:0016574 IEA histone ubiquitination
GO:0035064 IDA methylated histone binding
GO:0035098 IMP ESC/E(Z) complex
GO:0042054 IMP histone methyltransferase activity
GO:0043565 IEA sequence-specific DNA binding
GO:0045596 IMP negative regulation of cell differentiation
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052022 suz12b suppressor of zeste 12 homolog (Drosophila) b protein_coding Danio_rerio
ENSDARG00000070256 suz12a suppressor of zeste 12 homolog (Drosophila) a protein_coding Danio_rerio
ENSMUSG00000017548 Suz12 suppressor of zeste 12 homolog (Drosophila) protein_coding Mus_musculus

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