C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ets variant 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017724 Etv4 10090 - 11:101769742-101785371 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017868 Etv4-002 101769747-101785371 protein_coding
  ENSMUST00000107176 Etv4-001 101769747-101785371 protein_coding
  ENSMUST00000129160 Etv4-011 101773692-101784861 processed_transcript
  ENSMUST00000129995 Etv4-008 101773862-101784491 processed_transcript
  ENSMUST00000131117 Etv4-009 101774168-101784388 processed_transcript
  ENSMUST00000131862 Etv4-010 101773831-101785258 processed_transcript
  ENSMUST00000132040 Etv4-003 101770354-101772181 processed_transcript
  ENSMUST00000137179 Etv4-006 101774208-101785310 processed_transcript
  ENSMUST00000140970 Etv4-004 101774081-101785222 processed_transcript
  ENSMUST00000149099 Etv4-005 101774168-101785260 processed_transcript
  ENSMUST00000154512 Etv4-007 101784256-101784848 processed_transcript
  ENSMUST00000164750 Etv4-201 101769742-101785310 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017868ENSMUST00000107176ENSMUST00000129160ENSMUST00000129995ENSMUST00000131862ENSMUST00000132040ENSMUST00000137179ENSMUST00000140970ENSMUST00000149099ENSMUST00000154512ENSMUST00000164750
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017868 0.167±0.06 0.452±0.18 0.090±0.00 0.778±0.00 0.709±0.11 3.358±1.18 0.034±0.00 N/A 0.096±0.05 0.146±0.05 0.421±0.00 0.490±0.21 0.167±0.17 N/A
ENSMUST00000107176 0.166±0.11 0.378±0.12 0.054±0.00 0.779±0.00 0.828±0.15 2.747±1.08 N/A 0.297±0.09 0.043±0.02 0.112±0.04 N/A 0.438±0.22 0.157±0.06 0.156±0.02
ENSMUST00000129160 0.090±0.00 N/A N/A N/A N/A N/A 0.113±0.00 0.277±0.00 N/A N/A 0.597±0.00 N/A 0.684±0.00 N/A
ENSMUST00000129995 N/A N/A N/A N/A N/A N/A N/A N/A 0.200±0.00 N/A 0.766±0.00 N/A N/A N/A
ENSMUST00000131862 N/A N/A N/A N/A N/A N/A N/A N/A 0.052±0.00 N/A N/A 0.876±0.00 0.112±0.00 N/A
ENSMUST00000132040 N/A N/A N/A 1.239±0.48 N/A N/A 0.104±0.00 N/A 0.126±0.09 N/A 0.435±0.09 N/A 0.147±0.02 0.308±0.05
ENSMUST00000137179 0.213±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000140970 N/A N/A N/A N/A N/A N/A 0.147±0.00 N/A 0.042±0.00 N/A 0.319±0.00 N/A N/A N/A
ENSMUST00000149099 N/A 0.991±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.346±0.00 N/A N/A
ENSMUST00000154512 N/A 0.635±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000164750 N/A N/A N/A N/A N/A N/A 0.054±0.00 0.167±0.00 0.037±0.03 N/A N/A 0.610±0.51 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000996 CIL_000996_0002 VISTA 11:101501412-102102123
CIL_00090X CIL_00090X_0002 VISTA 11:101529827-102131014
CIL_000997 CIL_000997_0002 VISTA 11:101567301-102168287
CIL_000495 CIL_000495_0002 CGP 11:101732919-101785371
CIL_00048L CIL_00048L_0002 CGP 11:101769742-101894374

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 IDA DNA binding
GO:0005515 IEA protein binding
GO:0005622 IDA intracellular
GO:0005634 IBA nucleus
GO:0005730 IEA nucleolus
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0008045 IMP motor neuron axon guidance
GO:0010628 IDA positive regulation of gene expression
GO:0033600 IMP negative regulation of mammary gland epithelial cell proliferation
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048863 IMP stem cell differentiation
GO:0060444 IMP branching involved in mammary gland duct morphogenesis
GO:0060762 IDA regulation of branching involved in mammary gland duct morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018303 etv4 ets variant gene 4 protein_coding Danio_rerio
ENSG00000175832 ETV4 ets variant 4 protein_coding Homo_sapiens

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