C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAB5A, member RAS oncogene family
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017831 Rab5a 10090 + 17:53479234-53507671 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017975 Rab5a-201 53479234-53507671 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017975
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017975 8.143±0.58 7.152±2.09 30.529±0.79 19.122±4.59 6.154±1.03 8.528±1.44 8.079±0.15 10.334±1.18 11.514±3.67 13.589±0.58 15.286±1.68 9.044±6.85 22.962±6.28 3.817±0.95

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002VJ CIL_0002VJ_0003 CGP 17:53398889-53507671
CIL_0004HT CIL_0004HT_0002 CGP 17:53479234-53539451

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0003924 ISS GTPase activity
GO:0005515 IPI protein binding
GO:0005525 ISS GTP binding
GO:0005737 IDA cytoplasm
GO:0005768 IDA endosome
GO:0005769 IDA early endosome
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0006897 ISS endocytosis
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007399 IEA nervous system development
GO:0008021 ISS synaptic vesicle
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0015031 IEA protein transport
GO:0015629 IDA actin cytoskeleton
GO:0019001 IDA guanyl nucleotide binding
GO:0019003 ISS GDP binding
GO:0030139 IDA endocytic vesicle
GO:0030154 IEA cell differentiation
GO:0030424 ISS axon
GO:0030425 ISS dendrite
GO:0036465 IEA synaptic vesicle recycling
GO:0036477 IEA somatodendritic compartment
GO:0042589 IEA zymogen granule membrane
GO:0043005 IEA neuron projection
GO:0043025 ISS neuronal cell body
GO:0043195 ISS terminal bouton
GO:0043234 IEA protein complex
GO:0043679 ISS axon terminus
GO:0045022 IEA early endosome to late endosome transport
GO:0045121 IDA membrane raft
GO:0045335 IDA phagocytic vesicle
GO:0045921 IEA positive regulation of exocytosis
GO:0048169 IEA regulation of long-term neuronal synaptic plasticity
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051021 IEA GDP-dissociation inhibitor binding
GO:0051036 IEA regulation of endosome size
GO:0051489 IEA regulation of filopodium assembly
GO:0055037 IEA recycling endosome
GO:0070062 IEA extracellular vesicular exosome
GO:0098559 IEA cytoplasmic side of early endosome membrane
GO:2000286 IEA receptor internalization involved in canonical Wnt signaling pathway
GO:2000300 ISS regulation of synaptic vesicle exocytosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007257 rab5ab RAB5A, member RAS oncogene family, b protein_coding Danio_rerio
ENSG00000144566 RAB5A RAB5A, member RAS oncogene family protein_coding Homo_sapiens

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