C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis antagonizing transcription factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018697 Aatf 10090 - 11:84422855-84513522 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018841 Aatf-001 84422855-84513522 protein_coding
  ENSMUST00000127042 Aatf-004 84422883-84491550 processed_transcript
  ENSMUST00000141093 Aatf-003 84442509-84449533 retained_intron
  ENSMUST00000148434 Aatf-002 84466905-84513522 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018841ENSMUST00000127042ENSMUST00000148434
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018841 2.472±1.04 3.732±1.70 3.068±0.81 3.670±1.23 2.933±1.85 4.184±1.26 1.140±0.45 4.055±0.91 3.932±2.00 2.559±0.33 3.600±0.33 7.220±5.17 11.521±6.67 19.515±29.01
ENSMUST00000127042 N/A N/A N/A N/A 2.260±0.00 N/A 0.346±0.00 5.108±0.27 2.170±0.30 N/A N/A N/A 8.672±0.00 5.458±0.84
ENSMUST00000148434 N/A 1.026±0.25 N/A N/A 0.457±0.16 0.642±0.18 N/A N/A 0.569±0.14 0.530±0.17 N/A 1.593±0.89 0.757±0.08 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008GS CIL_0008GS_0002 VISTA 11:84076005-84677109
CIL_0008DP CIL_0008DP_0002 VISTA 11:84095730-84696774
CIL_00085M CIL_00085M_0002 VISTA 11:84181126-84782244
CIL_00085Q CIL_00085Q_0002 VISTA 11:84196288-84796920
CIL_0007ND CIL_0007ND_007N UCNEbase 11:84271978-84766400

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005813 IEA centrosome
GO:0005829 TAS cytosol
GO:0005925 IEA focal adhesion
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007155 IMP cell adhesion
GO:0007346 IMP regulation of mitotic cell cycle
GO:0019904 IEA protein domain specific binding
GO:0032929 IEA negative regulation of superoxide anion generation
GO:0040016 IMP embryonic cleavage
GO:0042254 IMP ribosome biogenesis
GO:0042985 IDA negative regulation of amyloid precursor protein biosynthetic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043522 IEA leucine zipper domain binding
GO:0044822 IEA poly(A) RNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048156 IEA tau protein binding
GO:2000378 IEA negative regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025467 aatf apoptosis antagonizing transcription factor protein_coding Danio_rerio
ENSG00000275700 AATF apoptosis antagonizing transcription factor protein_coding Homo_sapiens

Loading