C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: apoptosis antagonizing transcription factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000275700 AATF 9606 + 17:36948875-37056871 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000610798 AATF-006 36988658-37021154 protein_coding
  ENST00000613840 AATF-005 36949019-36988692 nonsense_mediated_decay
  ENST00000615319 AATF-002 37054827-37056870 retained_intron
  ENST00000616062 AATF-003 37054465-37056858 processed_transcript
  ENST00000616392 AATF-008 37018951-37056871 retained_intron
  ENST00000616434 AATF-007 36990775-37056870 protein_coding
  ENST00000617141 AATF-009 37031365-37056865 retained_intron
  ENST00000619387 AATF-001 36948875-37056871 protein_coding
  ENST00000622432 AATF-004 37051135-37056869 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000613840ENST00000619387ENST00000622432
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000613840 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 29.180±0.00 26.450±0.00 24.485±0.00
ENST00000619387 33.088±0.00 29.951±0.00 1.086±0.00 10.873±7.57 5.486±3.44 17.988±17.01 5.090±4.35 15.426±0.00 6.368±1.99 8.466±7.94 34.154±0.00 24.118±11.20 23.465±2.17 21.540±0.25
ENST00000622432 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.435±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00085R CIL_00085R_0001 VISTA 17:36355391-36956100
CIL_0007YB CIL_0007YB_0001 VISTA 17:36401446-37002205
CIL_0007YB CIL_0007YB_0003 VISTA 17:36402232-37002285
CIL_00085Q CIL_00085Q_0001 VISTA 17:36672050-37272645
CIL_00085M CIL_00085M_0001 VISTA 17:36678794-37279927
CIL_0008DP CIL_0008DP_0001 VISTA 17:36790335-37391543
CIL_0008GS CIL_0008GS_0001 VISTA 17:36817120-37418221
CIL_0005HW CIL_0005HW_0002 CGP 17:36936785-37056871
CIL_0007ND CIL_0007ND_005N UCNEbase 17:36943932-36968270
CIL_0005HT CIL_0005HT_0002 CGP 17:36948875-37406818

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005813 IDA centrosome
GO:0005925 IDA focal adhesion
GO:0006974 IEP cellular response to DNA damage stimulus
GO:0007155 IEA cell adhesion
GO:0007346 IEA regulation of mitotic cell cycle
GO:0019904 IEA protein domain specific binding
GO:0032929 IDA negative regulation of superoxide anion generation
GO:0040016 IEA embryonic cleavage
GO:0042254 IEA ribosome biogenesis
GO:0042985 IEA negative regulation of amyloid precursor protein biosynthetic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043522 IPI leucine zipper domain binding
GO:0044822 IDA poly(A) RNA binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048156 IEA tau protein binding
GO:0097190 TAS apoptotic signaling pathway
GO:2000378 IDA negative regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025467 aatf apoptosis antagonizing transcription factor protein_coding Danio_rerio
ENSMUSG00000018697 Aatf apoptosis antagonizing transcription factor protein_coding Mus_musculus

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