C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family A (ABC1), member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018800 Abca5 10090 - 11:110269369-110337716 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043961 Abca5-001 110269369-110337678 protein_coding
  ENSMUST00000124714 Abca5-002 110286819-110337622 protein_coding
  ENSMUST00000127318 Abca5-005 110309073-110337645 retained_intron
  ENSMUST00000134721 Abca5-004 110319807-110337640 protein_coding
  ENSMUST00000148984 Abca5-003 110325496-110337716 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043961ENSMUST00000124714
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043961 1.346±0.76 0.857±0.32 0.800±0.09 1.100±0.33 0.721±0.20 0.440±0.21 0.679±0.18 0.926±0.27 0.281±0.18 3.385±1.21 1.262±0.00 0.959±0.45 0.499±0.32 2.621±0.41
ENSMUST00000124714 N/A 0.897±0.06 N/A N/A 0.306±0.06 N/A N/A N/A 0.136±0.00 N/A N/A 0.475±0.13 N/A 1.438±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006H0 CIL_0006H0_0002 CGP 11:110269369-110525522

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005524 IEA ATP binding
GO:0005764 IDA lysosome
GO:0005770 IDA late endosome
GO:0005794 IEA Golgi apparatus
GO:0006200 IEA ATP catabolic process
GO:0010745 IMP negative regulation of macrophage derived foam cell differentiation
GO:0016021 IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0033344 IMP cholesterol efflux
GO:0034375 IMP high-density lipoprotein particle remodeling
GO:0043691 IC reverse cholesterol transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074041 abca5 ATP-binding cassette, sub-family A (ABC1), member 5 protein_coding Danio_rerio
ENSG00000154265 ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 protein_coding Homo_sapiens

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