C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family A (ABC1), member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154265 ABCA5 9606 - 17:69244311-69327244 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000392676 ABCA5-001 69244311-69327101 protein_coding
  ENST00000586601 ABCA5-014 69247376-69249141 retained_intron
  ENST00000586811 ABCA5-008 69248260-69268874 protein_coding
  ENST00000586995 ABCA5-006 69247346-69302849 nonsense_mediated_decay
  ENST00000587607 ABCA5-002 69306763-69327090 non_stop_decay
  ENST00000588106 ABCA5-013 69249288-69251628 retained_intron
  ENST00000588665 ABCA5-009 69313285-69327244 protein_coding
  ENST00000588877 ABCA5-004 69246951-69315425 protein_coding
  ENST00000589609 ABCA5-010 69316900-69327111 processed_transcript
  ENST00000589975 ABCA5-012 69304094-69309320 protein_coding
  ENST00000591234 ABCA5-007 69247145-69286261 nonsense_mediated_decay
  ENST00000592568 ABCA5-011 69309349-69327097 protein_coding
  ENST00000593153 ABCA5-003 69273971-69327182 protein_coding
  ENST00000593253 ABCA5-005 69306763-69315360 non_stop_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000392676ENST00000586601ENST00000586811ENST00000586995ENST00000588106ENST00000588877ENST00000591234ENST00000593153
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000392676 N/A N/A N/A 1.300±0.36 N/A 0.221±0.00 N/A 0.525±0.00 1.360±0.00 0.880±0.67 1.681±0.00 1.079±0.69 0.093±0.00 N/A
ENST00000586601 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.805±0.00 1.823±0.00 11.500±0.00
ENST00000586811 N/A N/A N/A N/A N/A N/A N/A 2.785±0.00 8.853±0.00 N/A 6.282±0.00 N/A N/A N/A
ENST00000586995 2.464±0.00 1.058±0.00 2.699±0.00 2.107±1.21 4.228±0.72 1.870±0.95 N/A 2.628±1.17 N/A 1.717±1.06 2.801±1.31 2.507±0.47 0.258±0.16 5.818±2.07
ENST00000588106 N/A N/A N/A N/A N/A 4.146±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000588877 1.317±0.00 0.779±0.00 2.042±0.00 1.396±0.52 2.421±0.39 2.391±0.00 0.908±0.15 2.269±1.27 N/A 1.644±0.00 2.051±0.04 1.571±0.51 0.198±0.00 N/A
ENST00000591234 N/A N/A N/A 2.078±0.35 N/A 0.922±0.00 0.902±0.00 1.246±0.00 6.276±0.00 2.082±1.11 5.679±0.00 3.479±1.74 0.595±0.32 7.468±2.19
ENST00000593153 N/A N/A N/A N/A N/A N/A 1.391±0.08 N/A N/A N/A 4.190±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006H0 CIL_0006H0_0001 CGP 17:69244311-69543331

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005764 ISS lysosome
GO:0005770 ISS late endosome
GO:0005794 IEA Golgi apparatus
GO:0006200 IEA ATP catabolic process
GO:0010745 ISS negative regulation of macrophage derived foam cell differentiation
GO:0016021 IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0033344 ISS cholesterol efflux
GO:0034375 ISS high-density lipoprotein particle remodeling
GO:0043691 IC reverse cholesterol transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074041 abca5 ATP-binding cassette, sub-family A (ABC1), member 5 protein_coding Danio_rerio
ENSMUSG00000018800 Abca5 ATP-binding cassette, sub-family A (ABC1), member 5 protein_coding Mus_musculus

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