C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SLIT-ROBO Rho GTPase activating protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020121 Srgap1 10090 - 10:121780991-122047315 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020322 Srgap1-001 121780991-122047308 protein_coding
  ENSMUST00000081688 Srgap1-201 121780991-122047315 protein_coding
  ENSMUST00000161156 Srgap1-004 121806640-121823133 protein_coding
  ENSMUST00000161996 Srgap1-003 121785240-121807104 processed_transcript
  ENSMUST00000162710 Srgap1-002 121895837-122047315 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020322ENSMUST00000081688ENSMUST00000161996
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020322 0.798±0.24 0.114±0.00 N/A 10.380±6.08 0.673±0.11 N/A 0.273±0.04 0.263±0.00 0.089±0.03 0.839±0.42 0.098±0.05 0.796±0.10 1.146±0.83 0.622±0.13
ENSMUST00000081688 1.891±0.93 N/A 1.160±0.09 N/A 0.531±0.22 1.605±0.42 0.186±0.05 0.841±0.16 0.266±0.08 1.145±0.37 N/A 1.003±0.38 2.573±0.56 0.489±0.00
ENSMUST00000161996 N/A N/A N/A N/A N/A N/A N/A N/A 0.069±0.02 N/A 0.081±0.00 N/A N/A 10.183±3.62

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YB CIL_0006YB_0002 CGP 10:121780991-122097371

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005100 IDA Rho GTPase activator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0007266 IDA Rho protein signal transduction
GO:0016477 IDA cell migration
GO:0017048 IDA Rho GTPase binding
GO:0032321 IDA positive regulation of Rho GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007461 srgap1 SLIT-ROBO Rho GTPase activating protein 1 protein_coding Danio_rerio
ENSDARG00000045789 srgap2b SLIT-ROBO Rho GTPase activating protein 2b protein_coding Danio_rerio
ENSG00000196935 SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 protein_coding Homo_sapiens

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