C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SLIT-ROBO Rho GTPase activating protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196935 SRGAP1 9606 + 12:63844293-64162221 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355086 SRGAP1-001 63844293-64162221 protein_coding
  ENST00000537556 SRGAP1-002 63844803-64081924 retained_intron
  ENST00000537585 SRGAP1-006 64111811-64116005 retained_intron
  ENST00000542381 SRGAP1-005 64042794-64043627 retained_intron
  ENST00000542841 SRGAP1-004 64127637-64142566 retained_intron
  ENST00000543397 SRGAP1-003 63982525-64143780 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355086ENST00000537556ENST00000542841ENST00000543397
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355086 0.615±0.00 1.027±0.00 0.268±0.00 0.120±0.03 0.407±0.14 0.325±0.00 0.041±0.01 N/A 0.180±0.08 0.380±0.06 0.046±0.00 0.583±0.18 0.158±0.11 0.598±0.00
ENST00000537556 N/A N/A 0.654±0.00 N/A 1.031±0.00 1.319±0.00 N/A 0.722±0.00 N/A 0.704±0.00 N/A 0.522±0.00 N/A 0.784±0.00
ENST00000542841 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.353±0.00 9.657±0.00
ENST00000543397 N/A N/A 0.492±0.00 0.451±0.03 0.765±0.00 0.668±0.00 0.199±0.06 N/A 0.551±0.00 0.673±0.33 0.080±0.05 0.407±0.00 0.225±0.05 1.244±0.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KR CIL_0002KR_0002 CGP 12:63844293-64222296

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005100 IEA Rho GTPase activator activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007266 IEA Rho protein signal transduction
GO:0007411 TAS axon guidance
GO:0016477 IEA cell migration
GO:0017048 IEA Rho GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0051056 TAS regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007461 srgap1 SLIT-ROBO Rho GTPase activating protein 1 protein_coding Danio_rerio
ENSDARG00000045789 srgap2b SLIT-ROBO Rho GTPase activating protein 2b protein_coding Danio_rerio
ENSMUSG00000020121 Srgap1 SLIT-ROBO Rho GTPase activating protein 1 protein_coding Mus_musculus

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