C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: E2F transcription factor 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000073781 E2f7-001 ENSMUSG00000020185 10090 + 10:110745468-110787384 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000073781
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000073781 0.038±0.00 0.196±0.13 0.054±0.00 0.699±0.71 0.149±0.03 0.268±0.06 0.041±0.01 0.034±0.01 0.597±0.74 0.140±0.07 0.040±0.02 0.656±0.52 5.168±5.06 0.392±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001227 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001890 IMP placenta development
GO:0002040 IMP sprouting angiogenesis
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0008285 IDA negative regulation of cell proliferation
GO:0030330 ISS DNA damage response, signal transduction by p53 class mediator
GO:0032466 IMP negative regulation of cytokinesis
GO:0032877 IMP positive regulation of DNA endoreduplication
GO:0042802 IEA identical protein binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0060707 IMP trophoblast giant cell differentiation
GO:0060718 IMP chorionic trophoblast cell differentiation
GO:0070365 IMP hepatocyte differentiation
GO:0071930 ISS negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:2000134 IDA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000007196 e2f7-201 protein_coding Danio_rerio 3e-30 139
ENSDART00000140760 e2f7-001 protein_coding Danio_rerio 3e-30 139
ENST00000322886 E2F7-001 protein_coding Homo_sapiens 0 2021
ENST00000416496 E2F7-004 protein_coding Homo_sapiens 0 1703
ENST00000550669 E2F7-003 protein_coding Homo_sapiens 0 1672
ENST00000551058 E2F7-007 protein_coding Homo_sapiens 0 671
ENST00000551558 E2F7-002 retained_intron Homo_sapiens 0 763
ENST00000552907 E2F7-006 nonsense_mediated_decay Homo_sapiens 0 797

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