C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, AMPA1 (alpha 1)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020524 Gria1 10090 + 11:57011387-57330244 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036315 Gria1-004 57011810-57330244 protein_coding
  ENSMUST00000094179 Gria1-005 57011956-57330243 protein_coding
  ENSMUST00000125292 Gria1-003 57011387-57015291 protein_coding
  ENSMUST00000151045 Gria1-006 57013046-57330240 protein_coding
  ENSMUST00000173531 Gria1-007 57176518-57189793 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036315ENSMUST00000094179ENSMUST00000151045ENSMUST00000173531
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036315 0.859±0.10 N/A 1.290±0.07 9.024±7.06 0.636±0.00 N/A 0.108±0.04 0.090±0.00 0.024±0.01 2.301±0.44 N/A 0.341±0.18 0.111±0.06 0.112±0.04
ENSMUST00000094179 0.057±0.07 0.068±0.03 N/A 17.399±18.11 0.358±0.13 0.098±0.04 N/A 0.038±0.02 0.024±0.01 N/A 0.030±0.00 1.268±0.08 0.005±0.00 0.020±0.00
ENSMUST00000151045 0.007±0.00 N/A 0.674±0.19 4.265±0.35 0.272±0.06 0.042±0.01 0.073±0.00 0.034±0.01 0.026±0.01 0.916±0.19 0.007±0.00 0.861±0.47 0.049±0.03 0.043±0.03
ENSMUST00000173531 N/A 0.212±0.09 N/A N/A 1.100±0.27 N/A N/A N/A N/A N/A N/A 2.794±0.00 N/A 0.468±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001UF CIL_0001UF_0002 CGP 11:56024987-57330244
CIL_0001UG CIL_0001UG_0002 CGP 11:57011387-57518617

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004971 IBA:ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0007268 IGI synaptic transmission
GO:0007616 IMP long-term memory
GO:0008021 IDA synaptic vesicle
GO:0008328 IDA ionotropic glutamate receptor complex
GO:0009986 IDA cell surface
GO:0014069 IDA postsynaptic density
GO:0016020 IDA membrane
GO:0030054 IEA cell junction
GO:0030425 IDA dendrite
GO:0031623 IMP receptor internalization
GO:0032281 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0032590 IDA dendrite membrane
GO:0034220 IBA ion transmembrane transport
GO:0035235 IBA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043197 IDA dendritic spine
GO:0044308 IDA axonal spine
GO:0044309 IDA neuron spine
GO:0045202 ISO synapse
GO:0045211 IEA:IDA postsynaptic membrane
GO:0060292 IGI long term synaptic depression

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021352 gria1a glutamate receptor, ionotropic, AMPA 1a protein_coding Danio_rerio
ENSDARG00000032714 gria1b glutamate receptor, ionotropic, AMPA 1b protein_coding Danio_rerio
ENSG00000155511 GRIA1 glutamate receptor, ionotropic, AMPA 1 protein_coding Homo_sapiens

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