C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribonucleotide reductase M2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020649 Rrm2 10090 + 12:24708241-24714146 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020980 Rrm2-001 24708241-24714146 protein_coding
  ENSMUST00000147789 Rrm2-002 24708556-24709589 retained_intron
  ENSMUST00000153058 Rrm2-003 24708752-24711769 protein_coding
  ENSMUST00000154588 Rrm2-004 24709029-24713341 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020980ENSMUST00000153058ENSMUST00000154588
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020980 1.714±1.20 1.262±0.09 1.792±0.13 10.946±8.37 1.791±1.46 3.417±1.51 0.575±0.08 0.759±0.25 55.657±63.80 0.724±0.26 0.311±0.10 3.452±1.83 32.861±22.39 2.846±0.99
ENSMUST00000153058 N/A N/A N/A 0.290±0.00 N/A N/A N/A N/A N/A N/A N/A 4.627±0.00 28.280±0.00 1.213±0.00
ENSMUST00000154588 N/A N/A N/A 0.163±0.00 N/A N/A N/A N/A N/A N/A 0.162±0.03 6.250±0.00 29.666±25.93 2.310±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007DI CIL_0007DI_0002 CGP 12:24665838-24714146

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004748 IDA ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006260 IEA DNA replication
GO:0009186 IEA deoxyribonucleoside diphosphate metabolic process
GO:0009262 IDA deoxyribonucleotide metabolic process
GO:0009263 IDA deoxyribonucleotide biosynthetic process
GO:0046872 IEA metal ion binding
GO:0051259 IPI protein oligomerization
GO:0051290 IPI protein heterotetramerization
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020711 rrm2 ribonucleotide reductase M2 polypeptide protein_coding Danio_rerio
ENSDARG00000078069 rrm2 ribonucleotide reductase M2 polypeptide protein_coding Danio_rerio
ENSG00000171848 RRM2 ribonucleotide reductase M2 protein_coding Homo_sapiens

Loading