C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tousled-like kinase 2 (Arabidopsis)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020694 Tlk2 10090 + 11:105178807-105283959 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015107 Tlk2-008 105181917-105282176 protein_coding
  ENSMUST00000092537 Tlk2-002 105181793-105276459 protein_coding
  ENSMUST00000106939 Tlk2-001 105178807-105283959 protein_coding
  ENSMUST00000106941 Tlk2-006 105181527-105282177 protein_coding
  ENSMUST00000123050 Tlk2-004 105207416-105240645 retained_intron
  ENSMUST00000126054 Tlk2-010 105180746-105209855 retained_intron
  ENSMUST00000126175 Tlk2-003 105181999-105282176 nonsense_mediated_decay
  ENSMUST00000134419 Tlk2-012 105246758-105247674 retained_intron
  ENSMUST00000145048 Tlk2-009 105181982-105276873 protein_coding
  ENSMUST00000146910 Tlk2-007 105252792-105271156 processed_transcript
  ENSMUST00000149459 Tlk2-011 105182217-105210558 protein_coding
  ENSMUST00000152404 Tlk2-005 105208853-105249486 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015107ENSMUST00000106941ENSMUST00000126054ENSMUST00000126175ENSMUST00000152404
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015107 1.995±0.00 N/A 8.257±0.00 10.320±1.72 N/A N/A N/A 2.125±0.03 6.589±4.91 2.633±0.00 2.469±0.36 6.447±1.12 10.264±4.61 22.743±2.94
ENSMUST00000106941 4.148±1.45 3.778±1.17 8.776±2.41 8.986±0.79 3.973±0.84 3.277±0.91 2.621±0.30 3.692±0.59 4.264±2.32 4.684±1.10 6.734±2.09 6.023±0.88 8.415±2.50 8.811±1.28
ENSMUST00000126054 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 87.683±0.00 125.784±0.00 408.568±0.00
ENSMUST00000126175 2.480±0.00 N/A 4.356±0.13 9.340±0.00 2.736±1.56 N/A 2.069±0.33 1.519±0.00 1.943±0.00 N/A 2.224±0.34 6.938±1.65 12.452±6.79 9.895±2.76
ENSMUST00000152404 N/A N/A N/A N/A 4.283±0.00 N/A N/A 5.406±0.00 3.785±0.19 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000563 CIL_000563_0003 CGP 11:105178807-105351139

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001672 ISS regulation of chromatin assembly or disassembly
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005634 ISS nucleus
GO:0005730 IEA nucleolus
GO:0005882 IDA intermediate filament
GO:0006468 ISS protein phosphorylation
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007049 IEA cell cycle
GO:0007059 ISS chromosome segregation
GO:0007275 IEA multicellular organismal development
GO:0007283 IEA spermatogenesis
GO:0016568 IEA chromatin modification
GO:0018105 ISS peptidyl-serine phosphorylation
GO:0030154 IEA cell differentiation
GO:0032435 ISS negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 ISS intracellular signal transduction
GO:0048471 IDA perinuclear region of cytoplasm
GO:0071480 IEA cellular response to gamma radiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010779 tlk2 tousled-like kinase 2 protein_coding Danio_rerio
ENSG00000146872 TLK2 tousled-like kinase 2 protein_coding Homo_sapiens

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